自动乳腺超声成像系统联合数字乳腺断层摄影对致密型乳腺内乳腺癌诊断价值分析

Analysis on the diagnostic value of ABUS combined with DBT in dense type of intra-mammary breast cancer

目的:探讨自动乳腺超声成像系统(ABUS)联合数字乳腺断层摄影(DBT)对致密型乳腺内乳腺癌诊断价值。方法:选取医院收治的96例致密型乳腺内乳腺癌患者,所有患者均在穿刺、手术等有创操作前1周内完成ABUS和DBT检查。以病理结果作为“金标准”,分析ABUS与DBT对致密型乳腺内乳腺癌的诊断价值。结果:96例患者经病理检查出96个病灶,以病理结果作为“金标准”,ABUS诊断致密型乳腺内乳腺癌的灵敏度、特异度及受试者工作特征(ROC)曲线下面积(AUC)分别为77.32%、82.53%和0.711(95%CI:0.635~0.792),DBT诊断致密型乳腺内乳腺癌的灵敏度、特异度及AUC分别为81.59%、80.23%和0.734(95%CI:0.612~0.776),ABUS联合DBT诊断致密型乳腺内乳腺癌的灵敏度、特异度及AUC分别为89.38%、92.46%和0.787(95%CI:0.659~0.824)。结论:ABUS联合DBT有利于提高致密型乳腺内乳腺癌临床检出率,减少肿块不伴钙化病灶的漏诊。

Objective:To explore the diagnostic value of automatic breast ultrasound imaging system(ABUS)combined with digital breast tomosynthesis(DBT)for dense type of intra-mammary breast cancer.Methods:A total of 96 patients with dense type of intra-mammary breast cancer who admitted to hospital were selected,and all patients completed ABUS and DBT examinations within 1 week before they underwent the invasive operations such as puncture and surgery.Taking pathological results as the gold standard,the diagnostic values of ABUS and DBT for dense type of intra-mammary breast cancer were analyzed.Results:A total of 96 lesions were detected out from 96 patients by pathological examination.Based on the pathological results as the gold standard,the sensitivity,specificity and area under curve(AUC)value of ROC of ABUS were respectively 77.32%,82.53%and 0.711(95%CI:0.635~0.792)in diagnosing dense type of intra-mammary breast cancer.The sensitivity,specificity and AUC value of DBT were respectively 81.59%,80.23%and 0.734(95%CI:0.612~0.776)in diagnosing that.The sensitivity,specificity and AUC of ABUS combined with DBT were respectively 89.38%,92.46%and 0.787(95%CI:0.659~0.824)in diagnosing that.Conclusion:ABUS combined with DBT is beneficial to improve the clinical detection rate of dense type of intra�mammary breast cancer,and reduce the missed diagnosis of tumor without company of calcification lesion.