摘要
In a recent study published in Nature,Zhang et al.explored the nutrient competition between cancer cells as well as their competition with macrophages during cancer development.1 Their data demonstrated that tumor-associated macrophage(TAM)can be dietarily or genetically reprogrammed to win in the competition with MYC-overexpressing cancer cells,providing new insights into our understanding of tumor development and immunotherapy.
基金
the National Natural Science Foundation of China(82241226,32170917)
Shanghai Original Exploratory Program(23ZR1481500).
