基于单分子荧光团构筑多色超分子组装体

Multi-color supramolecular assemblies constructed based on singlemolecule fluorophore

超分子组装体是基于分子间的非共价作用形成的具有一定结构和功能的聚集体,将其与多色荧光材料结合可实现其在生物成像、化学传感以及智能防伪材料等领域应用,因此,受到了科研工作者广泛关注.目前,多色荧光材料一般是通过结合多种荧光团的方式来实现不同颜色的构筑,但其需要进行多个不同荧光分子的制备,且合成复杂.而基于单一荧光分子制备多色超分子组装体的方法相对简单.只需制备一种荧光分子,而且合成相对容易且荧光颜色灵活可调.通过利用单分子荧光团构筑多色超分子组装体对于研究超分子自组装过程以及开发新型多色荧光功能体系具有重要意义.本文聚焦多色荧光超分子组装体的研究和发展现状,重点介绍了本课题组基于单分子荧光团制备的不同拓扑结构的多色超分子组装体及其功能应用并对该领域的未来发展进行了展望.

Supramolecular assemblies are aggregates of monomers formed by non-covalent interactions,which exhibit certain structures and functions.Combining them with multicolor fluorescent materials enables their applications in various fields such as biological imaging,chemical sensing,and intelligent anti-counterfeiting materials.Therefore,it has garnered great interest among researchers.Currently,multicolor fluorescent materials are generally prepared by incorporating multiple fluorescent groups,requiring the sophisticated synthesis of fluorescent molecules that involves cumbersome procedures.In contrast,the method based on a single fluorescent molecule to prepare multicolor supramolecular assemblies is relatively simple,for which one kind of fluorescent group synthesis could be available to achieve that.Taking advantage of the synthesis of a single fluorescent molecule only,this approach provides a more flexible tuning of the fluorescence color for supramolecular assemblies,offering rational design guidelines for novel multicolor fluorescent functional systems.This article focuses on the research and current development status of multicolor fluorescent supramolecular assemblies,and highlights the different topological structures of multicolor supramolecular assemblies prepared by our research group based on single fluorescent groups,as well as their functional applications.Lastly,this article provides an outlook for the promising future development in this field.