硬脂酰苯甲酰甲烷(SBM)合成工艺优化研究

Study on Optimization of Stearyl Benzoyl Methane(SBM)Synthesis Process

基于SBM工业化生产工艺路线,开展合成工艺优化研究实验,分析研究影响SBM收率及色泽的影响因素,并结合产品毛利率分析,得出经济效益最佳的反应物料配比。甲酯合成酯化工序需控制催化剂的加入量为硬脂酸投料量的15%,甲醇最低加量为理论量的1.5倍,生产中需严格把控硬脂酸原料的入厂品质检测;缩合反应控制需严格规范物料投料顺序,以滴加苯乙酮的方式控制反应,可防止苯乙酮自身的缩合副反应发生,确保SBM收率;在缩合反应过程中,需控制好反应温度,缩合反应温度最佳控制在125℃,反应物料配比为n(苯乙酮)∶n(硬脂酸甲酯)=1.0∶1.25,n(甲醇钠)∶n(苯乙酮)=1.5∶1.0,在此条件下SBM的收率在82.5%,色泽纯白,毛利率在34.19%。

Based on the industrial production process route of SBM,research experiments on synthesis process optimization were carried out to analyze the factors affecting the yield and color of SBM,and combined with the analysis of product gross profit rate,the optimal ratio of reaction materials with economic benefits was obtained.In the esterification process of methyl ester synthesis,the amount of catalyst added should be controlled to 15%of the feed amount of stearic acid,and the minimum add amount of methanol should be 1.5 times of the theoretical amount.Condensation reaction control should strictly regulate the feeding sequence of materials and control the reaction by drip adding acetophenone,which can prevent the condensation side reaction of acetophenone itself and ensure the yield of SBM.In the control process of the condensation reaction,it is necessary to control the stability of the reaction temperature,the optimal control of the condensation reaction temperature at 125℃,the n(acetophenone)∶n(methyl stearate)is 1.0∶1.25,n(sodium methanol)∶n(acetophenone)is 1.5∶1.0,under this condition,the yield of SBM is 82.5%,the color is pure white,and the gross profit rate is 34.19%.