一例新生儿化脓性脑膜炎个体化治疗的药学监护

Pharmaceutical care of a case of neonatal purulent meningitis treated individually

目的探讨临床药师在新生儿化脓性脑膜炎中抗感染方案个体化治疗的作用。方法临床药师从药物分布特点、科室病原菌回顾分析、用药原则及不良反应监护等方面提出个体化建议,患儿先后使用头孢哌酮舒巴坦、美罗培南、美罗培南+氟康唑、头孢克洛抗感染。结果临床药师通过个体化用药建议及药学监护,患儿病情好转,治疗19 d后患儿出院。结论临床药师参与新生儿化脓性脑膜炎的诊疗过程,有助于提高患儿用药的安全性和有效性。

Objective To explore the effect of clinical pharmacists in the individualized anti-infective treatment of neonatal purulent meningitis.Methods Clinical pharmacists put forward individual suggestions from the aspects of drug distribution characteristics,retrospective analysis of pathogenic bacteria in department,principle of drug use and monitoring of adverse reactions,the children were treated with cefoperazone sulbactam,meropenem,meropenem+fluconazole and cefaclor.Results Clinical pharmacists through individualized medication advice and pharmaceutical care,the children's condition improved,after 19 days of treatment,the children were discharged.Conclusion The participation of clinical pharmacists in the diagnosis and treatment of neonatal purulent meningitis is helpful to improve the safety and efficacy of medication.