基于中医传承辅助平台设计用于治疗鸡滑膜炎的中药组方分析

Design of traditional Chinese medicine prescriptions for treating chicken synovitis based on the traditional Chinese medicine inheritance platform

本研究基于中医传承辅助平台(V2.5),分析并总结中医药治疗滑膜炎的组方用药规律,设计能用于治疗鸡滑膜炎的中药组方。检索中国期刊全文数据库,筛选出治疗滑膜炎的口服中药处方总计768篇文献,运用中医传承辅助平台软件挖掘及无监督熵层次聚类分析,总结出处方高频用药的四气五味、常见配伍方式和其间的关联规则,拟定可用于治疗鸡滑膜炎的中药组方。纳入73首处方、116味中药,所用中药性味多为温寒平、苦甘辛,且多归为肝脾心肾四经,认为药物功效以活血化瘀和祛除湿邪为主。据此,拟定了8首可用于治疗鸡滑膜炎的中药复方。滑膜炎口服用药治疗可注重活血化瘀与祛除湿邪,同时可辅以调经止痛。

Based on the traditional Chinese medicine inheritance platform(V2.5),we analyzed and summarized the rules of prescriptions and medication of TCM for the treatment of chicken synovitis,and designed some Chinese medicine prescriptions that can be used to treat the synovitis.A total of 768 oral Chinese medicine prescriptions for this treatment were selected by searching the full-text database of Chinese journals.Using the software mining and unsupervised entropy hierarchical clustering analysis of the traditional Chinese medicine inheritance platform,we summarized the four qi and five tastes of prescriptions for high-frequency use,common combination patterns and the association rules among them,and developed Chinese medicine prescriptions that could be used to treat chicken synovitis.Seventy-three prescriptions and 116 Chinese herbal medicines were included,most of which were warm,cold,neutral,bitter,sweet and pungent in nature,were mostly classified into the four meridians of liver,spleen,heart and kidney,and were considered to be mainly effective in activating blood circulation and removing dampness.On these grounds,eight Chinese medicine prescriptions were developed for the treatment of chicken synovitis.The oral treatment of synovitis focused on invigorating blood stasis and eliminating dampness,and was supplemented by regulating menstruation and relieving pain.