血清维生素D与高血压及其治疗的研究进展

Research Progress in Relationship between Serum Vitamin D and Hypertension and Its Treatment

维生素D是一种脂溶性维生素,主要通过促进钙的吸收调节多种生理功能。高血压是一种病因复杂且具有进展性的心血管综合疾病,长期高血压可导致心力衰竭,极易引发急性缺血事件,增加患者死亡风险。近年发现维生素D不仅在人体钙、磷代谢中发挥重要作用,还与高血压的发病密切相关,血清维生素D水平降低可能导致高血压发生风险升高。维生素D与高血压的关联受到广泛关注,因此明确维生素D与高血压的相关性并进行量化,对改善心血管健康具有积极意义。

Vitamin D is a fat-soluble vitamin that regulates various physiological functions mainly by promoting calcium absorption.Hypertension is a comprehensive and progressive cardiovascular disease with a complex etiology.Long-term hypertension can lead to heart failure,which can easily trigger the acute ischemic events and increase the risk of death.In recent years,it has been found that vitamin D not only plays an important role in the calcium,phosphorus metabolism in human body,but also is closely related to the onset of hypertension.The decrease of serum vitamin D level may lead to an increased risk of hypertension.The association between vitamin D and hypertension has been widely concerned.Therefore,clarifying and quantifying the correlation between vitamin D and hypertension is of positive significance for improving cardiovascular health.