精准营养随访管理系统对CKD营养治疗效果的影响研究

Study on the effect of precision nutrition follow-up management system on nutrition therapy for CKD

目的 研究精准营养随访管理系统对慢性肾脏病(CKD)营养治疗效果的影响。方法 选取2021年3月至2022年4月该院肾内科收治的CKD 2~4期患者240例作为对象,采用分层随机法分为对照组和试验组,各120例。对照组营养治疗采用传统管理模式,试验组采用传统联合CKD精准营养随访管理系统干预模式。比较两组患者12个月后营养状况、实验室生化指标、心血管事件发生率与不良事件发生率等指标变化。结果 试验组患者营养状态优于对照组,SBP与DBP低于对照组,差异有统计学意义(P<0.05)。试验组患者血清肌酐增长值、肾小球滤过率(eGFR)下降值低于对照组,差异有统计学意义(P<0.05)。试验组患者尿素氮、血尿酸、糖化血红蛋白、血清总蛋白、清蛋白、前清蛋白、总胆固醇、甘油三酯、钾、钠、钙、磷、甲状旁腺素(PTH)等指标达标率高于对照组,差异有统计学意义(P<0.05)。心血管事件及不良事件发生率低于对照组差异有统计学意义(P<0.05)。结论 应用精准营养随访管理系统可以帮助CKD患者提高营养管理效率。

Objective To study the effect of precision nutrition follow-up management system on chronic kidney disease(CKD).Methods A total of 240 patients with stage 2-4 CKD admitted to the Department of Nephrology,Qianjiang Central Hospital of Chongqing from March 2021 to April 2022 were selected as the subjects,and were divided into the control group and the experimental group by random number table method,with 120 patients in each group.The control group adopted the traditional management mode of nutrition treatment,and the experimental group adopted the traditional management mode combined with CKD precision nutrition follow-up management system intervention mode.The changes of nutritional status,laboratory biochemical indexes,incidence of cardiovascular events and incidence of adverse reactions were compared between the two groups after 12 months.Results The nutritional status of the experimental group was better than that of the control group,and the SBP adn DBP was lower than that of the control group,with statisticalsignificance(P<0.05).The increase of serum creatinine and the decrease of glomerular filtration rate(eGFR) in the experimental groups were lower than those in the control group,and the difference was statistically significant(P<0.05).The compliance rates of urea nitrogen,blood uric acid,glycated hemoglobin,serum total protein,albumin,prealbumin,total cholesterol,triglyceride,potassium,sodium,calcium,phosphorus and parathyroid hormone(PTH) in the experimental group was higher than those in the control group,and the differences were statistically significant(P<0.05).The incidence of cardiovascular events and adverse reactions was significantly lower than those of the control group(P<0.05).Conclusion The application of precision nutrition follow-up management system can help improve the efficiency of nutrition management in CKD patients.