智慧化血糖管理平台模式对绝经后2型糖尿病合并骨质疏松患者糖代谢和骨代谢的影响

Effect of intelligent blood glucose management platform model on glucose metabolism and bone metabolism in postmenopausal patients with type 2 diabetes mellitus complicated with osteoporosis

目的 探讨智慧化血糖管理平台模式对绝经后2型糖尿病(T2DM)合并骨质疏松患者糖代谢和骨代谢的影响。方法 选择2022年1—9月湖州市中心医院就诊的90例绝经后T2DM合并骨质疏松患者,采用随机数字表法分为两组,每组各45例。对照组行常规T2DM合并骨质疏松管理,在对照组的基础上,观察组使用智慧化血糖管理平台模式。比较干预前、干预后两组自我管理能力水平(采用汉化自我管理能力量表评估)、糖代谢指标[空腹血糖(FBG)、餐后2 h血糖(2 h PG)、糖化血红蛋白(HbA1c)]、骨代谢指标[骨钙素(OST)、甲状旁腺激素(PTH)、降钙素(CT)]、骨密度T值(采用双能X线骨密度仪检测)。结果 干预后,观察组汉化自我管理能力量表总评分为(37.92±4.10)分,高于对照组的(34.38±4.35)分,差异有统计学意义(P<0.05)。干预后,观察组FBG[(6.84±1.52)mmol/L]、2 h PG[(8.14±1.46)mmol/L]、HbA1c[(6.14±0.41)%]及PTH[(63.12±3.82)pg/ml]水平均低于对照组[FBG(8.43±1.64)mmol/L、2 h PG(10.52±2.55)mmol/L、HbA1c(7.11±0.53)%、PTH(65.93±3.45)pg/ml],观察组OST[(8.05±0.36)μg/L]、CT[(20.08±4.72)ng/L]水平均高于对照组[OST(7.72±0.33)μg/L、CT(17.72±3.67)ng/L],差异均有统计学意义(P<0.05)。干预后,观察组骨密度T值(-2.41±0.06)高于对照组(-2.46±0.04),差异有统计学意义(P<0.05)。结论 将智慧化血糖管理平台模式应用于绝经后T2DM合并骨质疏松患者干预中,可有效增强患者自我管理能力,调节糖代谢与骨代谢指标水平,改善患者骨密度。

Objective To explore the effect of intelligent blood glucose management platform model on glucose metabolism and bone metabolism in postmenopausal patients with type 2 diabetes mellitus(T2DM) complicated with osteoporosis.Methods A total of 90 postmenopausal T2DM patients with osteoporosis who visited Huzhou Central Hospital from January to September 2022 were selected and divided into two groups by random number table method,with 45 cases in each group.The cases in control group received conventional management of T2DM combined with osteoporosis,and on the basis of conventional intervention,the cases in observation group were managed by intelligent blood glucose management platform model.The levels of self-management ability(assessed by Chinese self-management ability scale),glucose metabolism indexes [fasting blood glucose(FBG),2-hour postprandial blood glucose(2 h PG),glycosylated hemoglobin(HbA1c)],bone metabolism indexes [osteocalcin(OST),parathyroid hormone(PTH),calcitonin(CT)],and bone mineral density T value(detected by dual-energy X-ray absorptiometry) before and after intervention in the two groups were compared.Results After intervention,the total score of Chinese self-management ability scale in observation group was(37.92±4.10),which was higher than that in control group(34.38±4.35),and the difference was statistically significant(P<0.05).After intervention,the levels of FBG [(6.84±1.52)mmol/L],2 h PG [(8.14±1.46)mmol/L],HbA1c [(6.14±0.41)%],and PTH [(63.12±3.82)pg/ml] levels in observation group were lower than those in control group [FBG(8.43±1.64) mmol/L,2 h PG(10.52±2.55) mmol/L,HbA1c(7.11±0.53)%,PTH(65.93±3.45)pg/ml],OST [(8.05±0.36)μg/L] and CT [(20.08±4.72)ng/L] levels in observation group were higher than those in control group [OST(7.72±0.33) μg/L,CT(17.72±3.67) ng/L],the differences were statistically significant(P<0.05).After intervention,BMD T value in observation group was(-2.41±0.06),which was higher than that in control group(-2.46±0.04),and the difference was statistically significant(P<0.05).Conclusion Intelligent blood glucose management platform model used in the intervention of postmenopausal T2DM patients with osteoporosis can effectively enhance the patients' self-management ability,regulate the levels of glucose metabolism and bone metabolism indicators,and improve the patients' bone mineral density.