干细胞疗法在压力性尿失禁治疗中的应用

Application of stem cells therapy in the treatment of stress urinary incontinence

压力性尿失禁(stress urinary incontinence,SUI)是一种多种病因引起的不自主漏尿,在中年女性中发病率高,严重影响患者身心健康。SUI的治疗方式有生活方式治疗、药物治疗和手术治疗等,干细胞疗法因其可使受损组织再生的潜力,近年来在SUI的治疗中被广泛研究。本文讨论了用于治疗SUI的主要干细胞种类、相关治疗方式及临床试验进展。近年来脂肪源性干细胞、肌源性干细胞、骨髓源性干细胞和羊水源性干细胞等应用于SUI的治疗当中,多种治疗技术应用其中,实验研究和临床试验证明了干细胞的治疗效果。

Stress urinary incontinence(SUI)is a kind of involuntary urinary incontinence caused by various etiologies.It has a high incidence in middle-aged women and seriously affects the physical and mental health of patients.The treatment methods for SUI include lifestyle therapy,drug therapy and surgery.Stem cell therapy has been widely studied in the treatment of SUI in recent years due to its potential to regenerate damaged tissues.This article discusses the main types,treatment methods,clinical trials and other research progress of stem cell therapy for SUI.In recent years,adipose-derived stem cells,muscle-derived stem cells,bone marrow-derived stem cells and human amniotic fluid-derived stem cells have been applied to the treatment of SUI,and a variety of treatment techniques have been applied.Preclinical and clinical trials have shown the therapeutic effects of stem cells.