基于Web of Science数据库的急性肾损伤文献计量学分析

Bibliometric Analysis of Acute Kidney Injury Based on Web of Science Database

目的利用文献计量学方法对急性肾损伤领域进行研究,分析急性肾损伤的研究热点及现状,为临床和基础研究提供参考。方法收集Web of Science数据库建库至2021年的急性肾损伤相关文献,利用CiteSpace 6.1软件进行可视化分析。结果共收集文献41912篇文献,发文量呈逐年升高趋势;有158个国家、3112期刊参与急性肾损伤领域的研究,其中主要研究人群在美国及我国,Ronco C、Bellomo R、Kellum JA、Devarajan P为重要核心作者;研究机构以大学和医院为主,其中哈佛大学、匹兹堡大学为重要成员之一;发文量排名前3的期刊为Kidney International、PLoS One、American Journal of Physiology Renal Physiology;高频关键词为急性肾损伤的危险因素、结局、病因、基础研究、预后或预测风险因子及透析替代治疗研究,突增关键词有心脏衰竭、炎症、病理生理、保护、预测、预后等。结论急性肾损伤近年持续被重视,研究热点从肾脏替代治疗、危险因素筛选、基础实验转至不同病因中的病理生理、保护因素、预测指标的演变,对急性肾损伤的早期诊断、保护因素及预后评估仍为研究热点和难点。

Objective To study the field of acute renal injury by bibliometrics,and to analyze the research hotspot and current situation of acute renal injury,so as to provide reference for clinical and basic research.Methods Literatures related to acute kidney injury from the establishment of the Web of Science database to 2021 were collected,and Cite Space 6.1 software was used for visual analysis.Results A total of 41912 articles were collected,and the number of articles was increasing year by year.There were 158 countries and 3112 journals involved in the field of acute kidney injury research.The main research population was in the United States and China.Ronco C,Bellomo R,Kellum JA and Devarajan P were important core authors.The research institutions were mainly universities and hospitals,among which Harvard University and University of Pittsburgh were important members.The top 3 journals were Kidney International,PLoS One,American Journal of Physiology Renal Physiology.High frequency keywords included risk factors,outcome,etiology,basic research,prognosis or predictive risk factors,and dialysis replacement therapy research of acute kidney injury.The keywords with sudden increase included heart failure,inflammation,pathophysiology,protection,prediction,prognosis,etc.Conclusion Acute renal injury has been paid more and more attention in recent years,and the research focus has shifted from renal replacement therapy,risk factor screening and basic experiments to the evolution of pathophysiology,protective factors and predictive indexes in different etiology.The early diagnosis,protective factors and prognosis evaluation of acute renal injury are still hot and difficult.