摘要
预防乙型肝炎(乙肝)病毒母婴传播是控制慢性乙肝的关键。对所有乙肝表面抗原阳性母体的子代及时联合免疫预防,同时建议高病毒水平(HBV DNA>2×10^(5)U/mL)或乙肝e抗原阳性孕妇晚孕期服用抗病毒药物,母婴传播率可降至0.2%以下。全国普遍严格落实这些措施,是消除慢性乙肝的关键。
Prevention of mother-to-child transmission(MTCT)of hepatitis B virus(HBV)plays a critical role in the control of chronic HBV infection.The combined immunoprophylaxis in neonates of mothers with posi⁃tive hepatitis B surface antigen,plus antiviral therapy in the third trimester of pregnant women with high viral load(HBV DNA>2×10^(5)U/m L)or positive hepatitis B e antigen,can reduce MTCT to lower than 0.2%.Strict implementation of these measures in the whole country is the key to the elimination of chronic hepatitis B.
作者
唐洁
周乙华
TANG Jie;ZHOU Yi-hua(Department of Obstetrics and Gyne-cology,Wujin Hospital Affiliated to Jiangsu Universi-ty,Changzhou 213017,China;Department of Ob-stetrics and Gynecology,Wujin Clinical College of Xuzhou Medical University,Changzhou 213017,Chi-na;Departments of Laboratory Medicine and Ob-stetrics and Gynecology,Nanjing Drum Tower Hospi-tal,Nanjing University Medical School,Nanjing 210008,China)
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2023年第12期1185-1188,共4页
Chinese Journal of Practical Gynecology and Obstetrics
基金
国家自然科学基金(81672002)
江苏省自然科学基金(BK20221169)
南京市医学发展项目(ZKX20021)
江苏省妇产创新中心项目(CXZX202229)。
关键词
乙型肝炎
母婴传播
免疫预防
抗病毒药物
hepatitis B
mother-to-child transmis⁃sion
immunoprophylaxis
antiviral agent
