归逍方治疗早发性卵巢功能不全临证经验

Clinical Experience of Guixiao Fang in the Treatment of Premature Ovarian Insufficiency

早发性卵巢功能不全(POI)是妇科常见的内分泌疾病之一,发病率逐年增长并呈年轻化趋势。中医学中虽无此病名,但经历代医家总结,病变无不关乎肾肝脾三脏,各医家总结各自经验在临床上广泛应用,研究亦证实了中医药对治疗POI的疗效与安全性。杨正望教授治疗POI具有丰富的临床经验,认为肾虚肝郁证是POI的主要病机之一,疾病发展过程中肾虚肝郁影响脾胃功能,又会导致脾虚血弱,因此临床上以滋肾养阴、疏肝调经为主治疗。杨正望教授体会古籍、总结经验,将归肾丸与逍遥散合为归逍方治疗POI患者,肾亏得复、肝郁得解、血虚得养,达到改善患者月经情况、保护卵巢功能的目的。本研究总结归逍方治疗POI的临证经验,以期为临床治疗POI提供参考依据。

Premature ovarian insufficiency(POI)is one of the common endocrine diseases in gynecology.Its incidence rate is increasing year by year and the age of patients tends to be younger.There is no name for this disease in traditional Chinese medicine.However,it has been summarized through generations of doctors that the lesion is related to the kidney,liver and spleen,and their respective experiences were widely applied in clinical practice.Existing researches have also confirmed the efficacy and safety of traditional Chinese medicine in the treatment of POI.Professor Yang Zhengwang has rich experience in the treatment of POI.She believes that renal deficiency and liver stagnation is one of the main pathogenesis of POI.During the development of this disease,renal deficiency and liver stagnation affect the function of the spleen and stomach,leading to spleen deficiency and weak blood.Therefore,in clinical practice,enriching the kidney and replenishing yin,dispersing liver and regulating menstruation are the main treatment methods.Professor Yang Zhengwang learned from ancient books and summarized experience,and combined guishen wan and xiaoyao san into guixiao fang to treat POI patients.In this way,renal deficiency,liver stagnation and blood deficiency can be improved,achieving the goal of improving patients′menstrual conditions and protecting ovarian function.This study summarizes the clinical experience of using guixiao fang to treat POI,in order to provide reference for clinical treatment of this disease.