初治肿瘤患者参与临床试验心理体验的研究

Psychological experience of patients with primary tumors participating in clinical trials:a qualitative study

目的从患者视角深入了解初治肿瘤患者参加临床试验的心理体验,为针对性满足此类型患者心理需求,提升其心理健康水平提供参考依据。方法采用现象学研究方法,在2021年11月至2022年5月以目的抽样法选取13例初治肿瘤临床试验患者,进行半结构式访谈,并运用Colaizzi7步分析法对资料进行分析。结果初治肿瘤患者参加临床试验的心理体验提炼出4个主题:对临床试验的认知与态度体验,复杂多变的情绪反应,试验过程的适应,个人成长与转变。结论初治肿瘤患者参与临床试验的心理体验及相关心理问题不容忽视,研究团队需帮助其完成角色转换与适应,重视初治患者在试验参与中的体验,针对此类型患者需求完善心理健康教育方案,提升社会支持,进而提高初治肿瘤患者的生活质量,最终推动我国的肿瘤诊疗发展。

Objective To deeply understand the psychological experience of patients with primary tumors participating in clinical trials,providing a reference basis for meeting the psychological needs of patients and improving the mental health level of patients with primary tumors.Methods From November 2021 to May 2022,13 patients with primary tumors participating in clinical trials were selected by target sampling method,semi-structured interviews were conducted,with Colaizzi 7-step analysis method was used to analyze the data.Results Four themes were extracted from the psychological experience of patients,namely the perception and attitudinal experience of clinical trials,complex and changeable emotional responses,experimental process adaptation,personal growth and transformation.Conclusion The psychological experience and related psychological problems of primary tumors patients participating in clinical trials cannot be ignored,the research team needs to help them complete role transformation and adaptation,pay attention to the experience of patients,improve mental health education programs according to the needs of this type of patients,and improve the quality of life of patients,then promote the development of cancer diagnosis and treatment in China.