1例注射用奥美拉唑钠致过敏性休克病例的治疗分析

Treatment Analysis of One Case of Anaphylactic Shock Induced by Omeprazole Sodium for Injection

目的:探讨注射用奥美拉唑钠在临床应用过程中的药品不良反应,以提高其临床使用的合理性和安全性。方法:临床药师通过回顾性分析1例药物过敏性休克患者的临床资料,探究注射用奥美拉唑钠可能引起患者药物过敏性休克的原因。结果:注射用奥美拉唑钠可引起患者出现药物过敏性休克,引起药物过敏性休克的主要原因为超适应症用药。结论:临床在使用注射用奥美拉唑钠时,需详细询问患者过敏史,严格按照《质子泵抑制剂临床应用指导原则》适应症给药,遵守给药原则。

Objective:To probe into the adverse drug reactions in clinical application of omeprazole sodium for injection in order to improve the rationality and safety of its clinical use.Methods:Clinical pharmacists explored the possible causes of anaphylactic shock induced by omeprazole sodium for injection through retrospective analysis on the clinical data of one patient with drug anaphylactic shock.Results:Omeprazole sodium for injection can cause drug anaphylactic shock in patients,and the main cause of drug anaphylactic shock is off-label drug use.Conclusion:When using omeprazole sodium for injection,clinicians should ask patients about their allergic history in detail and prescribe according to indications specified in Guidelines for Clinical Use of Protein Pump Inhibitors and in compliance with administration guidelines.