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恒古骨伤愈合剂辅助肱骨近端内固定锁定系统治疗肱骨近端四部分骨折患者的效果 被引量:1

Effect of Henggu Bone Wound Healing Agent assisted with proximal humerus internal fixation locking system on patients with proximal humeral four-part fractures
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摘要 目的 观察恒古骨伤愈合剂辅助肱骨近端内固定锁定系统(PHILOS)治疗肱骨近端四部分骨折(FPFPH)患者临床效果。方法 将我院80例FPFPH患者随机分为观察组与对照组各40例。对照组采用PHILOS治疗,观察组采用恒古骨伤愈合剂辅助PHILOS治疗。比较两组术后1年的优良率、临床愈合率、骨性愈合率;Neer肩关节评分、肩部活动度;测定两组治疗前后碱性磷酸酶(ALP)、骨钙素(BGP)水平;记录两组术后1年并发症发生情况。结果 治疗后,观察组优良率高于对照组优良率(P<0.05);观察组临床愈合率、骨性愈合率高于对照组临床愈合率、骨性愈合率(P<0.05);术后1年两组Neer肩关节评分高于治疗前,观察组Neer肩关节评分高于对照组(P<0.05);两组肩部活动度增加,观察组肩部活动度高于对照组(P<0.05);两组ALP、BGP水平高于治疗前,观察组ALP、BGP水平高于对照组;两组并发症发生率无统计学意义(P>0.05)。结论 恒古骨伤愈合剂辅助PHILOS可促进FPFPH愈合,调节骨代谢指标,促进肩部功能恢复,安全性较好。 Objective To observe the effectiveness of Henggu Bone Wound Healing Agent assisted proximal humeral internal fixation locking system(PHILOS)in treatment of patients with proximal humeral four-part fractures(FPFPH).Methods Eighty patients with FPFPH were randomly divided into observation group and control group each of 40 cases.Control group was treated with PHILOS,while observation group was treated with Henggu Bone Wound Healing Agent as an adjunct to PHILOS.Compare the excellent and good rate,clinical healing rate,and bone healing rate of the two groups after 1 year of surgery;compare the Neer shoulder joint score and shoulder range of motion;detect the levels of serum alkaline phosphatase(ALP)and osteocalcin(BGP)before and after treatment in the two groups;record the incidence of complications 1 year after surgery in the two groups.Results After treatment,the excellent and good rate,the clinical healing rate and bone healing rate of observation group was higher than that of control group(P<0.05);1 year after surgery,the shoulder joint scores of both groups were higher than before treatment,and was higher in observation group than control group(P<0.05);the shouldermobility of both groups increased,and the increase was more obvious in observation group than control group(P<0.05);the levels of ALP and BGP in both groups were higher,and were higher in observation group than control group;there was no statistically significant difference in the incidence of postoperative complications between the two groups(P>0.05).Conclusion Henggu Bone Wound Healing Agent assisted PHILOS is effective in promoting FPFPH healing,regulating bone metabolism indicators,promoting shoulder function recovery with good safety.
作者 陈志超 张金堂 翁阳华 CHEN Zhi-chao;ZHANG Jin-tang;WENG Yang-hua(Dongguan Humen Hospital,Dongguan 523900)
出处 《湖北中医药大学学报》 2023年第6期89-91,共3页 Journal of Hubei University of Chinese Medicine
基金 广东省东莞市社会发展科技项目(项目编号:20211800902182) 广东省卫生健康委员会科研项目(项目编号:20190172)。
关键词 肱骨近端四部分骨折 恒古骨伤愈合剂 内固定锁定系统 Proximal humerus four-part fractures Henggu Bone Wound Healing Agent Internal fixation locking system
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