柴归汤加减治疗女大学生原发性痛经的效果观察

Observation on the Effect of Modified Chaigui Decoction on Primary Dysmenorrhea in Girl College Students

目的:分析柴归汤加减治疗女大学生原发性痛经的临床效果。方法:选取2021年3月—2022年3月在甘肃卫生职业学院附属医院门诊就诊的就读于甘肃卫生职业学院的原发性痛经患者为研究对象,共120例。以随机数字表法分为研究组和对照组,每组60例。研究组用柴归汤加减治疗,对照组给予吲哚美辛治疗。比较两组临床疗效、复发率、不良反应发生情况及治疗前后视觉模拟评分法(VAS)评分、COX痛经症状量表(CMSS)评分、中医症候积分、血清前列腺素指标。结果:两组总有效率比较,差异无统计学意义(P>0.05);治疗后研究组VAS评分、CMSS评分、中医症候积分及血清前列腺素指标均低于对照组(P<0.05);研究组不良反应发生率及复发率均低于对照组(P<0.05)。结论:柴归汤治疗女大学生原发性痛经的临床效果良好,复发率低,不良反应发生率低。

Objective:To analyze the clinical effect of modified Chaigui Decoction on primary dysmenorrhea in girl college students.Method:A total of 120 patients with primary dysmenorrhea who were enrolled in the Outpatient Department of Affiliated Hospital of Gansu Health Vocational College from March 2021 to March 2022and educated in Gansu Health Vocational College were selected as the study objects.They were divided into study group and control group according to random number table method,with 60 cases in each group.The study group was treated with modified Chaigui Decoction,and the control group was treated with Indometacin.The clinical efficacy,recurrence rate,occurrence of adverse reactions,visual analogue scale(VAS)score,COX menstrual symptom scale(CMSS)score,TCM symptom integration and serum prostaglandin indexes were compared between the two groups.Result:There was no significant difference in total effective rate between the two groups(P>0.05).VAS scores,CMSS scores,TCM symptom integrations and serum prostaglandin indexes of the study group were lower than those of the control group after treatment(P<0.05).The incidence of adverse reactions and recurrence in the study group were lower than those in the control group(P<0.05).Conclusion:Modified Chaigui Decoction has a good clinical effect on primary dysmenorrhea in girl college students,the recurrence rate is low,and the incidence of adverse reactions is low.