烷基多苷酒石酸酯的合成研究

Preparation of Alkyl Polyglycoside Tartrate

以烷基多苷为原料,采用两步法合成烷基多苷酒石酸酯。考察反应溶剂、反应物配比、反应温度和反应时间对烷基多苷马来酸酯和烷基多苷酒石酸酯的影响,并对目标产物进行红外表征。烷基多苷与顺丁烯二酸酐反应的优化条件为:以四氢呋喃为溶剂,顺丁烯二酸酐与烷基多苷的摩尔比为1∶1,反应温度95℃,反应时间3 h,合成收率为97.81%。烷基多苷马来酸酯与双氧水和甲酸的反应优化条件为:反应物配比(甲酸/双氧水与中间产物的摩尔比)为1.5∶1,反应温度为95℃,反应时间为3 h,最终目标产物的合成收率为85.56%。烷基多苷酒石酸酯的红外光谱图中出现了明显的羰基峰(1730.7 cm^(-1))。

Alkyl polyglycoside tartrate was synthesized by two-step method using alkyl polyglycoside as raw materials.The effects of reaction solvent,reactants ratio,temperature and time were studied on the synthesis of alkyl polyglycoside maleate and alkyl polyglycoside tartrate.The products were characterized by infra-red spectrum.The optimized reaction condition of alkyl polyglycoside and cis-butenedioic anhydride was as follows:the reaction solvent was furanidine,the mole ratio of cis-butenedioic anhydride and alkyl polyglycoside was 1∶1,the reaction temperature was 95℃and the reaction time was 3 h.The synthesis yield was 97.81%.The optimum synthesis condition of alkyl polyglycoside tartrate was as follows:the mole ration of and formic acid/hydrogen peroxide and alkyl polyglycoside maleate was 1.5∶1,the reaction temperature was 95℃and the reaction time was 3 h.The synthesis yield of the target product was 85.56%.The infra-red spectrum of alkyl polyglycoside tartrate confirmed its structure because the obvious carbonyl peak was found at 1730.7 cm^(-1).