水杨醛缩3,4,6-三甲氧基苯甲酰肼铜(Ⅱ)配合物的合成及表征

Synthesis and Characterization of Copper(II)complexes of 3,4,6-Trimethoxybenzoyl Hydrazide with Salicylaldehyde

基于酰腙类及其配合物较强的生物活性及稳定性,设计了将没食子酸甲基化、酯化、酰肼,然后与水杨醛结合形成配体与氯化铜反应,形成金属螯合物的合成路线;采用紫外、红外、原子吸收分光光度法以及电喷雾质谱(ESI-MS)对金属配合物进行结构表征。结果表明,配体的紫外(UV)吸收最高峰为264 nm,另外两个特征峰为326 nm与388 nm;红外(IR:KBr,cm^(-1)):v(OH)3060,v(C=O)1601,v(N-N)2872,v(C=N)1548,v(C-N)1317。酰腙配合物的紫外(UV)吸收最高峰为273 nm,另外两个特征峰为315 nm和385 nm;红外(IR:KBr,cm^(-1)):v(C=O)1527,v(N-N)3054,v(C=N)1463,v(C-N)1339;ESI-MS:理论值为793.11,实测值为793.945;原子吸收计算值(8.01±0.5)%,实测值8.4%。经过以上分析,可推测出该金属配合物的结构为双配体结构,符合最初的预想,具有一定的科研价值。

Based on the strong biological activity and stability of acylhydrazones and their complexes,a synthetic route was designed to methylate,esterify,hydrazide gallate,and then combine with salicylaldehyde to form a ligand and react with copper chloride to form a metal chelate;The metal complexes were characterized by UV,IR,AAS and ESI-MS.The results showed that the highest peak of UV absorption of the ligand was 264 nm,and the other two characteristic peaks were 326 nm and 388 nm;Infrared(IR:KBr,cm^(-1)):v(OH)3060,v(C=O)1601,v(N-N)2872,v(C=N)1548,v(C-N)1317.The highest UV absorption peak of the acylhydrazone complex is 273 nm,and the other two characteristic peaks are 315 nm and 385 nm;Infrared(IR:KBr,cm^(-1)):v(C=O)1527,v(N-N)3054,v(C=N)1463,v(C-N)1339;ESI-MS:Theoretical value is 793.11,measured value is 793.945;The calculated atomic absorption value is(8.01±0.5)%,while the measured value is 8.4%.After the above analysis,it can be inferred that the structure of the metal complex is a double ligand structure,which is in line with the initial expectation and has certain scientific research value.