老年2型糖尿病患者营养风险指数与骨密度的关系

Correlation between nutritional risk index and bone mineral density in elderly patients with type 2 diabetes

目的:探讨老年T2DM患者营养状况指标老年营养风险指数(GNRI)与骨密度的关系。方法:选择在医院就诊的208例老年T2DM患者,收集一般资料和临床数据,根据理想体质量和血清白蛋白水平计算GNRI。结果:所有T2DM患者根据DXA测量的结果被分为骨质疏松组和非骨质疏松组,骨质疏松组患者的GNRI评分明显低于非骨质疏松组,Pearson相关分析显示GNRI与骨密度成正相关。Logistic回归模型显示,GNRI是老年男性T2DM患者骨质疏松的独立危险因素(P<0.05)。结论:老年T2DM患者中GNRI与骨密度呈正相关,是识别糖尿病患者需要进行骨健康营养支持的良好指标。

Objective:To investigate the relationship between nutritional status indicators such as GNRI and bone mineral density in elderly patients with T2DM.Methods:A total of 208 elderly T2DM patients who were admitted to Hospital.General and laboratory data of the patients were collected.The GNRI was calculated based on ideal body weight and serum albumin levels.Result:All patients were also assigned to the non-osteoporosis and osteoporosis groups.The non-osteoporosis group had lower GNRI values than the osteoporosis group.Pearson's correlation analysis revealed that the GNRI was positively correlated with BMD(P<0.05).Regression analysis exhibited that the GNRI was significantly associated with osteoporosis.Conclusion:GNRI is positively correlated with bone mineral density in elderly T2DM patients,and is a significant indicator for identifying the need for further nutritional support for bone health in diabetic patients.