绝经后骨质疏松症与人体成分指标相关性初探

Preliminary Study on the Correlation between Postmenopausal Osteoporosis and Body Composition Indicators

目的:探讨绝经后骨质疏松症(PMOP)与人体成分分析指标的关系,从而为绝经后骨质疏松症的防治提供指导。方法:福清地区绝经后女性受试者144例,分为骨质疏松症组78例、非骨质疏松症组66例。采用双能X线吸收测定法(DXA)检测骨密度,用人体成分分析仪测定人体成分,并通过调查问卷登记受试者基本信息。采用独立样本t检验分析,了解绝经后骨质疏松症与体脂肪率、肌肉量、骨骼肌量及肌肉分布的相关性。结果:根据人体成分分析检测统计骨质疏松症组肌肉量小于非骨质疏松症组(P=0.032),骨骼肌量小于非骨质疏松症组(P=0.011)。骨质疏松症组身高、体重、体重指数及体脂肪率和非骨质疏松症组差异无统计学意义(P>0.05)。骨质疏松症组的骨骼肌/身高平方小于非骨质疏松症组(P=0.033),骨骼肌/肌肉量小于非骨质疏松症组(P=0.006)。在门诊为主体的受试者中,骨质疏松症组下肢肌肉评价低于非骨质疏松症组(P=0.026)。骨质疏松症组体脂肪率、肌肉量/身高平方、上肢肌肉评价、躯干肌肉评价与非骨质疏松症组差异无统计学意义(P>0.05)。结论:绝经后骨质疏松症与年龄、绝经年龄、肌肉量、骨骼肌量、肌肉情况分布相关。

Objective:To explore the relationship between postmenopausal osteoporosis(PMOP)and body composition analysis indicators,in order to provide guidance for the prevention and treatment of postmenopausal osteoporosis.Methods:144 postmenopausal female subjects in Fuqing area were divided into an osteoporosis group of 78 cases and a non osteoporosis group of 66 cases.Dualenergy X-ray absorptiometry(DXA)method was used to detect bone mineral density,human body composition was measured by using a body composition analyzer,and basic information of the subjects was recorded through a survey questionnaire.Using independent sample t-test analysis to understand the correlation between postmenopausal osteoporosis and body fat rate,muscle mass,skeletal muscle mass,and muscle distribution.Results:According to the analysis of human body composition,the muscle mass of the osteoporosis group is smaller than that of the non osteoporosis group(P=0.032),and the skeletal muscle mass is smaller than that of the non osteoporosis group(P=0.011).There was no significant difference in height,weight,body mass index(BMI),and body fat percentage between the osteoporosis group and the non osteoporosis group(P>0.05).The skeletal muscle/height square of the osteoporosis group is smaller than that of the non osteoporosis group(P=0.033),and the skeletal muscle/muscle mass is smaller than that of the non osteoporosis group(P=0.006).Among the outpatient subjects,the evaluation of lower limb muscles in the osteoporosis group was lower than that in the non osteoporosis group(P=0.026).There was no significant difference in body fat rate,muscle mass/height square,upper limb muscle evaluation,trunk muscle evaluation between the osteoporosis group and the non osteoporosis group(P>0.05).Conclusion:Postmenopausal osteoporosis is related to age,menopausal age,muscle mass,skeletal muscle mass,and muscle condition distribution.