炎症性肠病癌变的预防与监测

Prevention and monitoring of inflammatory bowel disease cancer

炎症性肠病的发病率居高不下,结肠炎相关结直肠癌作为炎症性肠病最严重的并发症之一,严重降低患者的生存质量。因此,需要对确诊为溃疡性结肠炎或克罗恩病的患者进行癌变高危因素管理,控制肠道慢性炎症,达到内镜及组织学缓解,并通过多种方法监测疾病进程,避免炎性相关结直肠癌及其他严重并发症的发生,从而提高患者的长期生活质量。

Theincidenceof inflammatory bowel diseaseremainshigh.Colitis-associated colorectal cancer,as one of the most serious complications of inflammatory bowel disease,seriously damages the patients'quality of life.Therefore,patients who diagnosed with ulcerative colitis or Crohn's disease need to be managed with risk factors for cancer,in order to control chronic intestinal inflammation,and achieve endoscopic and histological remission.Monitoring disease progression through a variety of methods to avoid the occurrence of inflammatory associated colorectal cancer and other serious complications can improve long-term quality of life for patients.