合并大血管侵犯的原发性肝细胞癌病人外放射治疗进展

Progress of external radiation therapy for patients with hepatocellular carcinoma complicated with macrovascular invasion

原发性肝细胞癌(HCC)病人确诊时常发现合并大血管侵犯(MVI),如门静脉瘤栓(PVTT)、肝静脉瘤栓(HVTT)及下腔静脉瘤栓(IVCTT)等。而大血管侵犯常预示着病人预后欠佳。目前可供选择的治疗方式多样,但缺少对伴有大血管侵犯的HCC治疗的专家共识。随着外放射治疗技术的发展,外放射治疗已成为HCC合并大血管侵犯的重要治疗手段之一。因此,现针对外放射治疗在合并大血管侵犯的肝细胞癌中的应用情况进行总结,以期为合并大血管侵犯的肝癌病人提供更多的治疗选择。

Patients with primary hepatocellular carcinoma(HCC)often have macrovascular invasion(MVI),such as portal vein tumor thrombus(PVTT),hepatic vein tumor thrombus(HVTT),and inferior vena cava tumor thrombus(IVCTT).MVI often predicts a poor prognosis for patients.Various treatment options are currently available,but there is a lack of expert consensus on the management of HCC with MVI.With the development of external radiotherapy technology,external radiotherapy has become an important treatment method for HCC complicated with MVI.Therefore,the application of external radiation therapy in HCC with MVI is summarized,in order to provide more treatment options for HCC patients with MVI.