高强度聚焦超声治疗子宫腺肌症的研究进展

Progress of high-intensity focused ultrasound in the treatment of uterine adenomyosis

子宫腺肌症是指子宫内膜腺体及间质侵入子宫肌层中,一般为弥漫性生长;常见于30~50岁妇女。子宫腺肌症的治疗包括药物治疗、手术治疗及微创治疗,其中高强度聚焦超声(HIFU)是一种微创治疗手段,目前已用于多种妇科疾病的治疗。其原理是通过皮肤贴合的体外治疗探头,在不损伤毗邻组织的前提下,将能量汇聚于靶区,产生一系列的效应,使靶区组织变性、坏死,以达到治疗目的。目前对其治疗只能是充分了解子宫腺肌症的临床症状,尽量早期诊断,临床干预,对症治疗,改善预后。现对HIFU治疗子宫腺肌症进行简要概述。

Adenomyosis(AM)refers to the presence of endometrial glands and stroma into the myometrium,generally diffuse growth.It is common in women aged 30-50 years old.The treatment of AM of the uterus includes drug treatment,surgical treatment and mini⁃mally invasive treatment.Among them,high-intensity focused ultrasound(HIFU)is a minimally invasive treatment method,that has been used for the treatment of various gynecological diseases.The principle is that through the skin-fitted in vitro treatment probe,in the premise of not damaging the adjacent tissue,the energy is concentrated in the target area,resulting in a series of effects,degenera⁃tion and necrosis of the target area tissue,so as to achieve the purpose of treatment.At present,the treatment for AM can only be based on a thorough understanding of its clinical symptoms,early diagnosis,clinical intervention,symptomatic treatment,and improvement af⁃ter recovery.Here is a brief overview of HIFU in the treatment of AM from the perspective of HIFU to relieve clinical symptoms of AM.