五运六气与干燥综合征发病特点及中医证候的相关性研究

Research on Relationship Between Five Yun and Six Qi and the PathogenesisCharacteristics of Primary Sj gren’s Syndrome and Its Syndromes of TCM

目的:探讨原发性干燥综合征(pSS)患者出生时的五运六气等相关信息与pSS发病所累及的系统损害及中医证候的相关性。方法:采用回顾性研究方法,从门诊及住院部收集2020年1月—2021年12月就诊的pSS患者,收集其出生时的运气学相关信息资料,统计运、气因素出现的频次,分析其与pSS发病所累及的系统损害及中医证候相关的运气因素,并运用中医理论进行分析、总结、探讨。结果:岁运因素中“土不及”是pSS患者的易患禀赋因素;岁运因素中“土不及”、六气因素中的“太阴司天、太阳在泉”及“厥阴司天、少阳在泉”是pSS气阴两虚证的易患禀赋因素;岁运因素中“土不及”“木太过”“金太过”“水太过”“水不及”,六气因素中“少阴司天、阳明在泉”及“少阳司天、厥阴在泉”为阴虚津亏证pSS的易患禀赋因素;岁运因素中“火太过”,六气因素中“太阴司天、太阳在泉”“少阴司天、阳明在泉”是阴虚热毒证pSS的易患禀赋因素;岁运因素中“木太过”“金不及”“木不及”,六气因素中“厥阴司天、少阳在泉”为阴虚血瘀证pSS的易患禀赋因素;岁运因素中“土不及”“金不及”,六气因素中“太阴司天、太阳在泉”为pSS患者关节受累的易患禀赋因素;岁运因素中“土不及”“金不及”为pSS患者肺受累的易患禀赋因素;岁运因素中“火太过”“土太过”“土不及”,六气因素中“厥阴司天、少阳在泉”为pSS患者血液系统受累的易患禀赋因素。结论:原发性干燥综合征的发病特点及其中医证候与五运六气具有一定的相关性。

Objective:To explore the relationship between Five Yun and Six Qi of birth and TCM syndromes and system damage involved in primary Sj gren’s Syndrome(pSS).Methods:The retrospective study method was used to collect the patients with pSS from the outpatient department and inpatient department from January 2020 to December 2021,collected the information of Yun-Qi of birth,counted the frequency of the Yun and Qi,analyzed the system damage involved in the onset and TCM syndromes of pSS related to the Yun-Qi factors,summarized and discussed them with the theory of TCM.Results:“Lack of soil”was the predisposing factor of pSS patients.The predisposing factors of pSS with Qi-Yin Deficiency Syndrome were“Taiyin-sitian,Taiyang-zaiquan”,“Jueyin-sitian,Shaoyang-zaiquan”and“Lack of soil”.The predisposing factors of pSS with Yin deficiency and depletion of fluid syndrome were“Lack of soil”,“Superabundance of wood”,“Superabundance of gold”,“Superabundance of water”,“Lack of water”,and“Shaoyin-sitian,Yangming-zaiquan”,“Shaoyang-sitian,Jueyin-zaiquan”.The predisposing factors of pSS with Yin deficiency heat toxin syndrome were“Superabundance of fire”,and“Shaoyin-sitian,Yangming-zaiquan”,“Taiyin-sitian,Taiyang-zaiquan”.The predisposing factors of pSS with Yin deficiency and blood stasis syndrome were“Superabundance of wood”,“Lack of gold”,“Lack of wood”,and“Jueyin-sitian,Shaoyang-zaiquan”.The predisposing factors of pSS patients’joint involvement were“Lack of soil”,“Lack of gold”,and“Taiyin-sitian,Taiyang-zaiquan”.The predisposing factors for lung involvement in pSS patients were“Lack of soil”,“Lack of gold”.The predisposing factors for the blood system involvement of pSS patients were“Superabundance of fire”,“Superabundance of soil”,“Lack of soil”,and“Jueyin-sitian,Shaoyang-zaiquan”.Conclusion:The characteristics of primary Sj gren’s Syndrome and its TCM Syndromes were related to the Five Yun and Six Qi.