江苏省常州市居民血脂比与糖尿病及糖尿病前期的关系

Relationship of diabetes and prediabetes with lipid ratios in Changzhou Residents of Jiangsu Province

【目的】探讨江苏省常州市35~75岁居民血脂比与糖尿病及糖尿病前期的关联性。【方法】采用多阶段整群随机抽样方法,调查常州市天宁区和武进区35~75岁常住居民,通过问卷调查、体格检查和实验室检测获得相关数据。采用二分类logistic回归方法分析血脂比与糖尿病及糖尿病前期的关系。【结果】调查人群中糖尿病患病率为18.69%,糖尿病前期患病率为10.53%;总人群中TC/HDL‐C、TG/HDL‐C和LDL‐C/HDL‐C比值最高组人群患糖尿病前期风险均显著增加,分别增加68%、93%和38%;TC/HDL‐C、TG/HDL‐C和LDL‐C/HDL‐C最高组患糖尿病风险也显著增加,分别增加105%、149%和78%。与男性相比,女性3项血脂比上升均导致糖尿病和糖尿病前期的患病风险增加,关联性较强。【结论】35~75岁人群中血脂比TC/HDL‐C、TG/HDL‐C以及LDL‐C/HDL‐C与糖尿病及糖尿病前期风险存在关联性,其中TG/HDL‐C与糖尿病及糖尿病前期的关联性最强,有望成为评估糖尿病发生发展的重点预测指标。

[Objective]To investigate the association of lipid ratios with diabetes and pre-diabetes in residents aged 35-75 years in Changzhou City.[Methods]A multistage whole-group random sampling method was used to survey permanent residents aged 35-75 years in Tianning and Wujin districts of Changzhou City,and the study data were obtained by questionnaires,physical examination and laboratory tests.The relationship between lipid ratios and diabetes and pre-diabetes was analyzed by dichotomous logistic regression method.[Results]The prevalence of diabetes in the surveyed population in Changzhou was 18.69%,and the prevalence of pre-diabetes was 10.53%.In the total population,the risk of pre-diabetes was significantly increased in the highest TC/HDL-C,TG/HDL-C and LDL-C/HDL-C groups,by 68%,93% and 38%,respectively;the risk of diabetes was also significantly increased in the highest TC/HDL-C,TG/HDL-C and LDL-C/HDL-C groups,by 105%,149% and 78%,respectively.The risk of diabetes was also significantly increased in the highest TC/HDL-C,TG/HDL-C and LDL-C/HDL-C groups,by 105%,149% and 78%,respectively.All three lipid ratios increased in women compared to men,leading to a stronger association with increased risk of diabetes and pre-diabetes.[Conclusion]Lipid ratios TC/HDL-C,TG/HDL-C,and LDL-C/HDL-C were correlated with the risk of diabetes and pre-diabetes in people aged 35-75 years,with TG/HDL-C having the strongest association with diabetes and pre-diabetes,and is expected to be a key predictor for assessing the development of diabetes.