卡瑞利珠单抗致少见免疫相关外展神经不良反应的药学监护

Pharmaceutical care of rare immune-related abducens nerve adverse events induced by camrelizumab

临床药师参与2例由卡瑞利珠单抗引发外展神经不良反应的多学科团队协作诊治。临床药师识别、分析外展神经不良反应发生原因并进行药学监护,及时停用卡瑞利珠单抗,进行规范糖皮质激素治疗,同时对患者进行药学监护及用药教育。最终患者临床症状得到缓解。临床药师通过全程参与卡瑞利珠单抗相关外展神经不良反应的管理,在治疗团队中提供药学监护以及为后续治疗提出个体化治疗方案发挥重要作用,有利于提高患者药物治疗的安全性和有效性。

Clinical pharmacists participated in the multiple disciplinary team treatment of 2 patients with immuno-associated abducens nerve palsy induced by camrelizumab.The clinical pharmacist identified and analyzed the causes of adverse reactions,timely suggested stopping camrelizumab and provided standardized treatment of glucocorticoid and summarized the treatment recommendations.Finally,the patients symptoms relieved significantly.Clinical pharmacists play an important role in the treatment of immunoassociated abducens nerve palsy induced by camrelizumab,suggestions on pharmaceutical care are provided for clinical drug use,to help improve the safety and efficacy of drug treatment.