乳腺浸润性导管癌MRI表现与其病理学分级和预后的关系

MRI manifestations of breast invasive ductal carcinoma and their relationship with pathological grade and prognosis

目的 探究乳腺浸润性导管癌磁共振成像(MRI)表现与其世界卫生组织(World Health Organization,WHO)病理学分级和预后的关系。方法 回顾性分析宝鸡市中心医院2019年3月至2021年3月经病理学活检确诊的93例乳腺浸润性导管癌患者,所有患者进行MRI检查,分析MRI表现与病理学分级和预后的关系。结果 病理学分级越高肿瘤直径越大、肿瘤形态越趋于分叶形及不规则形、内部强化趋于不均匀及边缘强化、表观扩散系数(apparent diffusion coefficient,ADC)值越低(P<0.05);预后不良患者肿瘤直径越大、肿瘤形态越趋于分叶形及不规则形、内部强化趋于不均匀及边缘强化、ADC值越低(P<0.05);肿瘤大小、内部强化特点以及ADC值是预后的影响因素(P<0.05)。结论 乳腺浸润性导管癌患者MRI表现与病理学分级及预后密切相关,临床应依据MRI表现评估患者病情与预后。

Objective To explore the magnetic resonance imaging(MRI)manifestations of breast invasive ductal carcinoma,and their relationship with World Health Organization(WHO)pathological grade and prognosis.Methods This study retrospectively reviewed 93 patients with breast invasive ductal carcinoma confirmed by pathological biopsy in Baoji Central Hospital between March 2019 and March 2021.All patients underwent MRI examination.The relationship of MRI manifestations with pathological grade and prognosis was analyzed.Results The higher the pathological grade,the longer the tumor diameter,the more lobulated and irregular the tumor morphology,the more heterogeneous the internal and marginal enhancement,and the lower the apparent diffusion coefficient(ADC)value(P<0.05).Tumor size,internal enhancement and ADC value were prognostic factors(P<0.05).Conclusion MRI manifestations are related to pathological grade and the prognosis of patients with breast invasive ductal carcinoma,which provides reference for condition evaluation and prognosis.