磁共振加速器治疗局部晚期直肠癌的初步经验

Magnetic resonance linac for locally advanced rectal cancer:a preliminary experience

磁共振加速器作为一种新型的放射治疗设备,应用于直肠癌的经验较少报道。本文介绍了磁共振加速器治疗直肠癌的步骤,并报告了使用该步骤治疗6例局部晚期直肠癌的初步治疗结果。6例直肠肿瘤均退缩,其中2例(2/6)可达肿瘤完全消退,所有患者放疗期间未出现3度以上毒副反应。每次放疗实施前,MR图像显示解剖、靶区清晰,可顺利实现在线自适应放疗和实时跟踪放疗。磁共振加速器在直肠癌放疗方面具有良好的应用前景。

As an emerging radiation therapy modality,experience with magnetic resonance linac(MR-Linac)for rectal cancer is rarely reported.This article introduces a procedure for the treatment of rectal cancer with MR-Linac and reports the preliminary results of the treatment of 6 cases of locally advanced rectal cancer using this procedure.All of the rectal tumors regressed,with 2 cases(2/6)achieving complete tumor regression,and no≥G3 acute toxicities occurred during radiation therapy.Before the implementation of each radiotherapy,MR image shows the anatomy and target volume clearly,which can successfully realize online adaptive radiotherapy and real-time tracking radiotherapy.MR-linac has a good prospect in the radiotherapy of rectal cancer.