虫媒病毒感染传播及跨界免疫适应机制

Infection, Transmission, and Cross-kingdom Immune Adaption of Arboviruses

基于第323期“双清论坛”,本文在介绍虫媒病领域的研究背景下,从媒介生物学、虫媒病毒学和病毒—虫媒—宿主互作三个方面梳理了我国在医学、动物及植物虫媒病毒领域的研究进展,涉及病毒感染媒介的分子机制、虫媒病毒的免疫互作机制、病毒跨界传播机制以及虫媒病健康绿色防控的新方法,凝练出该领域亟需解决的关键科学问题,提出我国未来5~10年虫媒病领域的发展目标。

Based on the 323rd Shuangqing Forum,we review the research progress on arboviruses for medicine,animals and plants in China,including vector biology,arbovirology,and virus-vector-host interaction.This review discusses the mechanisms of viral infection,immune interaction and crosskingdom transmission,and new healthy and green methods for prevention and control of vector-borne diseases.The key scientific questions in the area of vector-borne diseases and developmental objectives in the next 5-10 years are summarized and brought forward.