肝海绵状血管瘤经肝动脉平阳霉素碘油乳剂介入治疗的应用效果分析

Analysis of the Application Effect of Transhepatic Artery Pingyangmycin Iodine Oil Emulsion Intervention for Hepatic Cavernous Hemangioma

目的 研究经肝动脉平阳霉素碘油乳剂介入治疗肝海绵状血管瘤的具体方法及临床疗效。方法 随机选取2020年1月—2022年12月宁德师范学院附属宁德市医院收治的50例肝海绵状血管瘤患者为研究对象,通过随机数表法分为常规组和观察组,每组25例。常规组使用血管瘤剥除术治疗,观察组使用经肝动脉平阳霉素碘油乳剂介入治疗,比较两组患者治疗效果。结果 两组患者临床治疗有效率比较,差异无统计学意义(χ~2=0.000,P>0.05);治疗后,观察组白蛋白高于常规组,直接胆红素、谷草转氨酶、谷丙转氨酶低于常规组,差异有统计学意义(P<0.05);观察组手术时间、切口长度、术中出血量、术后1周肝区常态下疼痛评分、术后1周肝区压迫状态下疼痛评分均低于常规组,差异有统计学意义(P<0.05);观察组并发症发生率(4.00%)低于常规组,差异有统计学意义(χ~2=4.878,P<0.05)。结论 肝海绵状血管瘤患者实施经肝动脉平阳霉素碘油乳剂介入治疗,具有较好的治疗效果,且临床指标均优于常规方法,患者并发症更少,肝功能指标改善效果更好,疼痛相对较轻。

Objective To study the specific methods and clinical efficacy of transhepatic artery Pinyangmycin iodine oil emulsion intervention for hepatic cavernous hemangioma.Methods 50 patients with hepatic cavernous hemangioma admitted to Ningde Municipal Hospital of Ningde Normal University from January 2020 to December 2022 were randomly selected as the study objects,and were divided into conventional group and the observation group by the method of randomized numerical table,with 25 cases in each group.The conventional group was treated with hemangioma debulking surgery,and the observation group was treated with transhepatic artery pingyangmycin iodine oil emulsion intervention.And the therapeutic effects of the two groups were compared.Results There was no statistically significant difference in clinical efficacy between the two groups(χ~2=0.000,P>0.05).After treatment,albumin in observation group was higher than that of the conventional group,and direct bilirubin,aspartate aminotransferase,and alanine aminotransferase were lower than those of the conventional group,the differences were statistically significant(P<0.05).The operation time,incision length,intraoperative bleeding,postoperative 1-week pain score in the normal state of the liver area,and postoperative 1-week pain score in the state of pressure in the liver area in observation group were lower than those of the conventional group,the differences were statistically significant(P<0.05).The complication rate in observation group was 4.00%,which was lower than that in the conventional group,the difference was statistically significant(χ~2=4.878,P<0.05).Conclusion By implementing transhepatic artery pingyangmycin iodine oil emulsion intervention for patients with hepatic cavernous hemangioma,it can have a better therapeutic effect,and all kinds of clinical indexes are better than the conventional method,with fewer complications in patients,better improvement of hepatic function indexes and relatively less pain.