腹部CT诊断为囊肿患者2559例的回顾性研究

A retrospective study of 2559 patients with cysts diagnosed by abdominal CT

目的探讨腹腔囊肿患者发生肿瘤的风险。方法对重庆市中医院2019年2月至2020年1月2559例腹部CT诊断囊肿的患者进行回顾性研究,采用二分类logistic回归方法分析腹部CT诊断为囊肿患者发生肿瘤的风险,并分析肝囊肿、肾囊肿、脾囊肿患病风险在年龄与性别上是否具有差异。结果2559例患者中左肾囊肿2405例(94.0%),右肾囊肿2272例(88.8%),肝囊肿1167例(45.6%),双肾囊肿903例(35.3%),合并肿瘤625例(24.4%),脾囊肿7例(0.3%)。相关性分析显示,双肾囊肿与左肾囊肿、右肾囊肿呈正相关(r=0.619、0.688);回归分析显示,性别、脾囊肿、肾囊肿、肝囊肿对于肿瘤的患病风险差异无统计学意义(P>0.05),年龄差异有统计学意义[比值比(OR)=1.015,95%可信区间(95%CI)1.008~1.022,P<0.001];性别(OR=0.727,95%CI 0.570~0.928,P=0.011)、年龄(OR=1.041,95%CI 1.031~1.052,P<0.001)、肝囊肿(OR=0.001,95%CI 0.000~0.005,P<0.001)对于肾囊肿的患病风险,差异有统计学意义;对于肝囊肿的患病风险,仅有肾囊肿因素差异有统计学意义(OR=0.001,95%CI 0.000~0.005,P<0.001)。结论囊肿不是肿瘤的危险因素;女性较男性更容易患肾囊肿,随着年龄的增加患肾囊肿的风险增加。

Objective To investigate the risk of tumor occurrence in the patients with abdominal cyst.Methods A retrospective study was performed on 2559 patients with cysts from February,2019 to January,2020 of Chongqing Municipal Hospital of Traditional Chinese Medicine diagnosed by abdominal CT.The binary logistic regression method was adopted to analyze the risk of tumor occurrence in the patients with cyst diagnosed by abdominal CT.Then whether the occurrence risk of liver cyst,renal cyst and spleen cyst having the differences in age and sex was analyzed.Results Among 2559 cases,there were 2405 cases(94.0%)of left renal cyst,2272 cases(88.8%)of right renal cyst,1167 cases(45.6%)of hepatic cyst,903 cases(35.3%)of double renal cysts,625 cases(24.4%)of complicating tumor and 7 cases(0.3%)of splenic cyst.The correlation analysis showed that the double renal cysts were positively correlated with left renal cyst and right renal cyst(r=0.619,0.688);the regression analysis showed that gender,splenic cyst,renal cyst and hepatic cyst had no statistically significant difference in the risk of tumor occurrence(P>0.05),while the age factor had a statistically significant difference(OR=1.015,95%CI 1.008-1.022,P<0.001);gender(OR=0.727,95%CI 0.570-0.928,P=0.011),age(OR=1.041,95%CI 1.031-1.052,P<0.001)and hepatic cyst(OR=0.001,95%CI 0.000-0.005,P<0.001)had a statistically significant difference in the occurrence risk of renal cyst;for the occurrence risk of hepatic cyst,only the difference in renal cyst factor had statistical significance(OR=0.001,95%CI 0.000-0.005,P<0.001).Conclusion Cyst is not a risk factor for tumor.Female is more likely to suffer from renal cyst than male,and the risk of renal cysts occurrence is increased with age increase.