肾绞痛药物的选择

Choice of Drugs for Renal Colic

肾绞痛典型的临床表现为肾区隐痛或剧烈疼痛,严重影响患者生活质量。镇痛是肾绞痛患者的第一需求,药物治疗是肾绞痛疼痛管理的重要方式。阿片类药物(如吗啡和哌替啶)可有效缓解肾绞痛的疼痛,但由于其成瘾性和不良反应等问题,仅在必要时短期使用。非甾体抗炎药(如双氯芬酸钠)可缓解轻至中度疼痛,且相对安全。而解痉药(如间苯三酚)可在缓解疼痛的同时促进结石排出。因此,未来全面了解肾绞痛药物的治疗选择,可以为疾病的治疗提供新思路。

The typical clinical manifestation of renal colic is dull pain or severe pain in renal area,which seriously affects the quality of life of the patients.Analgesia is the first demand of the patients with renal colic,and drug treatment is an important way to manage the pain of renal colic.Opioid drugs(such as morphine and pethidine)can effectively relieve the pain of renal colic,but because of their addiction and adverse reactions,they are only used for a short time when necessary.Non-steroidal anti-inflammatory drugs(such as diclofenac sodium)can relieve mild to moderate pain and are relatively safe.Spasmodic drugs(such as phloroglucinol)can relieve pain and promote the discharge of stones at the same time.Therefore,a comprehensive understanding of the treatment options of renal colic drugs in the future can provide new ideas for the treatment.