期刊文献+

经口低温等离子在扁桃体癌切除中的疗效分析

Effect analysis of transorallow-temperature plasma in tonsil carcinoma resection
下载PDF
导出
摘要 目的探讨经口低温等离子技术在扁桃体癌切除术中的疗效。方法回顾性分析2018年12月至2021年5月就诊于南京鼓楼医院耳鼻咽喉头颈外科就诊和治疗的16例扁桃体癌患者的临床资料。所有患者均行经口低温等离子扁桃体癌切除术,8例患者术后行同步的放疗和化疗,3例仅行放疗,1例仅行化疗,均定期复查。分析术后患者吞咽、呼吸、发声功能等情况及远处转移情况。结果所有患者均成功施行手术,术后均无严重并发症,局部及颈部淋巴结无复发,未见远处转移。均可正常进食,无呛咳,无吞咽困难等;复查喉镜无咽瘘,口咽部疤痕增生,咽腔无狭窄,发音良好。除1例患者化疗后骨髓抑制,右上肢静脉血栓外,其余11例患者均愈后良好,无并发症。结论经口低温等离子切除扁桃体癌术后恢复良好,咽腔结构保留完好,不影响正常功能,值得临床推广。 Objective To investigate the effect of transoral low-temperature plasma technique in tonsil carcinoma resection.Methods The clinical data of 16 patients with tonsil cancer who were treated in the Department of Otolaryngology,Head and Neck Surgery of Nanjing Drum Tower Hospital from December 2018 to May 2021 were retrospectively analyzed.All patients underwent transoral low-temperature plasma resection of tonsil carcinoma.8 patients received simultaneous radiotherapy and chemotherapy,3 patients received radiotherapy only,and 1 patient received chemotherapy only.All patients were reviewed regularly.The swallowing,breathing,vocal function and distant metastasis were analyzed.Results All patients were successfully operated without serious complications,no recurrence of local and cervical lymph nodes,and no distant metastasis.All of them could eat normally without choking or dysphagia.Reexamination laryngoscope showed no pharyngeal fistula,oropharyngeal scar hyperplasia,pharyngeal cavity stenosis and good pronunciation.Except for 1 patient with myelosuppression and right upper limb venous thrombosis after chemotherapy,the other 11 patients recovered well without complications.Conclusion Transoral low-temperature plasma resection of tonsil carcinoma has good recovery,and the structure of pharyngeal cavity is intact,without affecting the normal function,which is worthy of clinical promotion.
作者 肖倩 刘丁丁 顾亚军 沈晓辉 钱晓云 孙振 张亚萍 王俊国 XIAO Qian;LIU Dingding;GU Yajun;SHEN Xiaohui;QIAN Xiaoyun;SUN Zhen;ZHANG Yaping;WANG Junguo(Department of Otolaryngology Head and Neck Surgery,Nanjing Drum Tower Hospital Clinical College of Jiangsu University,Nanjing 210008,Jiangsu,China;Department of Otolaryngology Head and Neck Surgery,Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University,Research Institute of Otolaryngology,Nanjing 210008,Jiangsu,China)
出处 《医学研究与战创伤救治》 北大核心 2023年第9期940-943,共4页 Journal of Medical Research & Combat Trauma Care
基金 南京大学中国医院改革发展研究院课题项目(南京鼓楼医院医学发展医疗救助基金会资助项目)(NDYG2020031)。
关键词 扁桃体癌 低温等离子 p16+ 预后 tonsil cancer low-temperature plasma p16+ prognosis
  • 相关文献

参考文献4

二级参考文献60

  • 1周梁,丁彭,王薇.喉癌术后局部复发与手术切缘的关系[J].临床耳鼻咽喉科杂志,2004,18(6):339-340. 被引量:14
  • 2姚远洋,赵昀,王建六,魏丽惠.宫颈癌石蜡标本中人乳头状瘤病毒检测方法的初步探讨[J].现代妇产科进展,2007,16(2):96-99. 被引量:5
  • 3Chenevert J, Chiosea S. Incidence nf human papillomavims in oropharyngeal squamous cell carcinomas: now and 50 years ago [J]. Hum Pathol,2012,43( 1 ) :17-22.
  • 4Nasman A, Attner P, Hammarstedt L, et al. hmidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockhohn, Sweden: an epidemic of viral-induced carcinoma [ J ]. Int J Cancer,2009,125 (2) :362-366.
  • 5Palmer E, Newcombe RG, Green AC, et al. Human papillomavirus infection is rare in nonmalignant tonsil tissue in the UK: implications for tonsil cancer precursor lesions [ J ]. Int J Cancer, 2014,135 (10) :2437-2443.
  • 6Klaes R, Friedrieh T, Spitkovsky D, et al. Overexpression of p16 (1NK4A) as a specific marker for dysplastie and neoplastic epithelial cells of the cervix uteri [ J ]. lnt J Cancer,2001,92 (2) : 276-284.
  • 7Mehanna H, Beech T, Nicholson T, et al. Prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer--systematic review and meta-analysis of trends by time and region[ J]. Head Neck ,2013,35 (5) :747-755.
  • 8Li W ,Tran N, Lee SC, et al. New evidence for geographic variation in the role of human papillomavirus in tonsillar carcinogenesis[ J]. Pathology ,2007,39 (2) :217-222.
  • 9D'Souza G, Kreimer AR, Viscidi R, et al. Case-control study of human papillomavirus and orophatyngeal cancer [ J ]. N Engl J Med ,2007,356 ( 19 ) : 1944-1956.
  • 10Song JS, Kim MS, Park JW, et al. Expression of human papillomavirus-related proteins and its clinical implication in tonsillar squamous cell carcinoma [ J ]. Korean J Pathol, 2012,46 f2) :177-186.

共引文献49

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部