正念在肺癌患者癌症复发恐惧与生活质量的中介效应研究

Mediating effect of mindfulness on the relations between fear of cancer recurrence and quality of life in patients with lung cancer

目的探讨正念水平在癌症复发恐惧与生活质量间的中介效应。方法采用便利抽样法,选取2022年1月至2023年1月山西省3所三级甲等综合医院收治的240例肺癌患者为调查对象,采用一般资料调查表、癌症患者恐惧疾病进展简化量表、中文版正念注意觉知量表、欧洲癌症研究会生活质量测定量表进行横断面调查,采用Pearson相关性分析癌症复发恐惧与生活质量间的相关性,采用Bootstrap法模型分析正念水平在两者的中介效应。结果本研究共发放240份问卷,收回217份,有效回收率为96.42%。肺癌患者的癌症复发恐惧处于中等水平,与正念水平、生活质量呈负相关(r=-0.348,P<0.01;r=-0.331,P<0.01)。Bootstrap分析显示,患者正念是癌症复发恐惧与生活质量的中间变量,且25.68%是通过正念水平途径介导的。结论肺癌患者癌症复发恐惧与生活质量呈负相关,且癌症复发恐惧可能通过提高患者正念水平来提高肺癌患者生活质量。

Objective To investigate the mediating effect of mindfulness on the relations between FCR and QOL.Methods A total of 240 lung cancer patients who were admitted to 3 hospitals in Shanxi Province,from January 2022 to January 2023,were enrolled in the study by convinient sampling.The fear of progression questionnaire-short form(FoP-Q-SF),mindfulness attention awareness scale(MAAS)in Chinese and the European Organisation for Research and Treatment for Cancer Quality of life questionnaire(EORTC QLQ)were employed in the cross-sectional survey.Multiple linear regression was used to analyse the association between FCR and QOL,and Bootstrap Model was adopted to analyse the mediating effect of mindfulness between FCR and QOL.Results A total of 240 questionnaires were distributed and 217 of them were retrieved,with an effective retrieval rate of 96.42%.FCR was found at a moderate level in all lung cancer patients,and it was negatively associated with the mindfulness and QOL(r=-0.348,P<0.01:r=-0.331,P<0.01).Bootstrap analysis revealed that the changes in mindfulness score acted as an intermediate variable between FCR and QOL,mediating 25.68%of the relationship.Conclusions FCR in lung cancer patients is negatively associated with QOL.This association may be explained by the reduction in mindfulness experienced by the patients.