浙江省成年居民代谢综合征流行特征及三种不同诊断标准的对比研究

Epidemiological characteristics and comparison of three diagnostic criteria on metabolic syndrome in adult residents of Zhejiang Province

目的掌握浙江省成年居民代谢综合征(MetS)的流行特征,比较不同诊断标准在浙江省成年居民中应用的差异及一致性。方法本研究为横断面研究。利用2018年中国慢性病及危险因素监测项目中浙江省10个国家慢性病危险因素监测点的数据,采用多阶段分层整群抽样,通过问卷调查、身体测量、实验室检测等方法获得调查对象的人口学基本信息和慢性病患病等情况。对数据进行复杂加权后,分析和比较浙江省成年居民在不同诊断标准下代谢综合征的流行现状。结果共纳入成年居民5369人,男性2411人,女性2958人。采用JIS、CDS和IDF诊断标准MetS的患病率依次为33.62%、25.32%和24.25%。IDF标准和JIS标准诊断的一致率最高,为89.11%,Kappa值为0.768(P<0.001);IDF标准和CDS标准的诊断一致率次之,为84.53%,Kappa值为0.631(P<0.001),JIS标准和CDS标准的一致率最低,为83.17%,Kappa值为0.621(P<0.001)。CDS诊断标准下,MetS的患病率与性别、婚姻状况、吸烟、饮酒等行为因素有关。结论浙江省成年居民MetS的患病率处于较高水平,IDF标准和JIS标准诊断MetS的一致性最高,应加强对MetS的筛查,尽早发现高危人群,减少心脑血管疾病和糖尿病的发病风险,提高居民的生活质量。

Objective To understand the epidemiological characteristics of metabolic syndrome(MetS)among adult residents in Zhejiang Province and compare three diagnostic criteria in adult residents.Methods In this cross-sectisnal study participants were randomly chosen using multi-stage stratified cluster sampling method from 10 national chronic disease risk factor monitoring sites in Zhejiang Province of the 2018 China Chronic Disease and Risk Factors Surveillance Project.Demographics and information on chronic disease prevalence were obtained through questionnaire,physical measurements,and laboratory.After complex weighting of the data,an analysis and comparison of the prevalence of MetS under different diagnostic criteria among adult residents in Zhejiang Province was conducted.Results A total of 5369 adult residents were included,2411 males and 2958 females.The prevalence of MetS using JIS,CDS and IDF diagnostic criteria was 33.62%,25.32%,and 24.25%,respectively.The consistency rate between IDF and JIS was the highest(89.11%)and the Kappa value was 0.768(P<0.001).The consistency rate between IDF and CDS diagnostic criteria was 84.53%,and the Kappa value was 0.631(P<0.001).The consistency rate between JIS and CDS was the lowest(83.17%),and the Kappa value was 0.621(P<0.001).Under CDS diagnostic criteria,the prevalence of MetS was associated to gender,marital status,smoking and drinking.Conclusion The prevalence of MetS is at a relatively high level among adult residents in Zhejiang province.The consistency between IDF and JIS diagnostic criteria is the highest.Screening for MetS should be strengthened to detect high-risk individuals early,reduce the risk of cardiovascular and cerebrovascular diseases and diabetes,and improve the quality of life of residents.