脑电生物反馈治疗联合盐酸哌甲酯治疗注意缺陷多动障碍患儿的效果

Effects of EEG biofeedback therapy combined with Methylphenidate hydrochloride in treatment of children with attention deficit hyperactivity disorder

目的:观察脑电生物反馈治疗联合盐酸哌甲酯治疗注意缺陷多动障碍(ADHD)患儿的效果。方法:选取2021年1月至2022年12月该院收治的60例ADHD患儿进行前瞻性研究,按照随机数字表法将其分为对照组和研究组各30例。对照组口服盐酸哌甲酯治疗,研究组在对照组基础上联合脑电生物反馈治疗,两组均连续治疗3个月。比较两组临床疗效,治疗前后儿童行为问题[Conners父母问卷(PSQ)]评分、视听整合持续测试系统(IVA-CPT)评分、睡眠质量[匹兹堡睡眠质量指数(PSQI)]评分,以及不良反应发生率。结果:研究组治疗总有效率为93.33%(28/30),高于对照组的70.00%(21/30),差异有统计学意义(P<0.05);治疗后,研究组品德问题、学习问题、心神障碍、冲动-多动、焦虑、多动指数等PSQ各项评分和PSQI评分均低于对照组,差异有统计学意义(P<0.05);治疗后,研究组综合注意力商数、综合反应控制商数等IVA-CPT评分均高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:脑电生物反馈治疗联合盐酸哌甲酯治疗ADHD患儿可提高治疗总有效率和IVA-CPT评分,降低儿童行为问题评分,改善睡眠质量,效果优于单纯盐酸哌甲酯治疗。

Objective:To observe effects of EEG biofeedback therapy combined with Methylphenidate hydrochloride in treatment of children with attention deficit hyperactivity disorder(ADHD).Methods:A prospective study was conducted on 60 children with ADHD admitted to this hospital from January 2021 to December 2022.According to the random number table method,they were divided into control group and study group,30 cases in each group.The control group was treated with oral Methylphenidate hydrochloride,while the study group was treated with EEG biofeedback on the basis of that of the control group.Continuous treatment lasted for 3 months.The clinical efficacy,the children’s behavioral problems[Conners parents questionnaire(PSQ)]score,the audiovisual integration continuous test system(IVA-CPT)score,the sleep quality[Pittsburgh sleep quality index(PSQI)]score before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the study group was 93.33%(28/30),which was higher than 70.00%(21/30)in the control group,and the difference was statistically significant(P<0.05).After the treatment,the PSQ scores of moral problems,learning problems,mental disorders,impulse-hyperactivity,anxiety and hyperactivity index and the PSQI score in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the IVA-CPT scores such as comprehensive attention quotient and comprehensive response control quotient in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:EEG biofeedback therapy combined with Methylphenidate hydrochloride in the treatment of the ADHD children can improve the total effective rate of treatment and the IVA-CPT scores,reduce the children’s behavioral problem scores,and improve the sleep quality.Moreover,it is superior to single Methylphenidate hydrochloride treatment.