乳腺富于脂质癌的探讨

Investigation of lipid-rich carcinoma of the breast

乳腺富于脂质癌(LRC)于1963年被首次描述,该疾病已被重新分配到无特殊类型浸润性乳腺癌类别中。有研究者认为乳腺LRC癌细胞中的脂质是乳腺导管上皮细胞分泌产物。LRC的病理特征是质地坚硬,切片呈淡黄色,与周围组织边界不清。乳腺LRC通常被认为是乳腺癌的侵袭性表型,其缺乏统一的治疗方案和标准。更深入的随访研究将有助于制定综合治疗方案。该文评述了乳腺LRC的研究过程和发展现状。

Lipid-rich carcinoma(LRC)of the breast was first described in 1963,and is now considered an invasive breast carcinoma of no special type(IBC-NST).Some researchers believe that the lipid content of cancer cells in LRC is secreted by ductal epithelial cells of the breast.The pathological features of LRC include hard texture,light yellow sections,unclear boundaries with surrounding tissues.LRC is generally considered an invasive phenotype of breast cancer,no consensus has been reached regarding treatment regimen and standard for LRC.Further follow-up studies will help to develop comprehensive treatment plans.In this article,the research process and development status of LRC were reviewed.