不同年龄段健听人颈性前庭诱发肌源性电位参数的研究

The Potential Parameters of Cervical Vestibular Evoked Myogenic Potential in Normal Subjects of Different Ages

目的探讨颈性前庭诱发肌源性电位在不同年龄段健听人群中的正常参考值范围。方法将60例健康志愿者分为儿童组和成人组,利用丹麦WDH集团的Eclipse客观听觉测试平台分别进行颈性前庭诱发肌源性电位测试,对数据进行统计学分析。结果两组中左侧和右侧间P1、Nl潜伏期、P1-N1波间期、振幅、不对称比均无显著差异;两组中男性和女性间P1、Nl潜伏期、P1-N1波间期、振幅、不对称比均无显著差异;儿童组中P1正常值范围为13.97±1.46 ms,N1正常值范围为21.82±1.85 ms,振幅正常范围为100.71±91.17μV,波间期正常范围为7.85±1.12 ms;成人组中P1正常值范围为16.11±2.23 ms,N1正常值范围为24.66±2.35 ms,振幅正常范围为61.26±27.74μV,波间期正常范围为8.58±1.48 ms;两组之间P1、Nl潜伏期、P1-N1波间期、振幅均有显著差异(P<0.05),不对称比无显著差异。结论颈性前庭诱发肌源性电位的波形及参数与侧别、性别无相关性,潜伏期、波间期随年龄增长而延长,振幅随年龄的增长而减小。

Objective To investigate the range of normal reference values of cervical vestibular evoked myogenic potentials in different age groups.Methods Sixty healthy volunteers were divided into children group and adult group,and the cervical vestibular myogenic potential was tested by Eclipse objective auditory test platform of WDH Group,and the data were analyzed statistically.Results Statistical results showed that there were no significant differences in P1 latency,Nl latency,P1-N1 wave interval,amplitude and asymmetry ratio between the left and right sides of the two groups.There were no significant differences in P1 latency,Nl latency,P1-N1 wave interval,amplitude and asymmetry ratio between the male and female groups.In the children group,the normal range of P1 and N1 was 13.97±1.46 ms,21.82±1.85 ms,the normal range of amplitude was 100.71±91.17μV,and the normal range of wave interval was 7.85±1.12 ms.In the adult group,the normal range of P1 and N1 was 16.11±2.23 ms,24.66±2.35 ms,the normal range of amplitude was 61.26±27.74μV and and the normal range of wave interval was 8.58±1.48 ms.There were significant differences in P1 latency,Nl latency,P1-N1 interval and amplitude between the two groups,but no significant differences in asymmetry ratio.Conclusion The waveform and parameters of cervical vestibular myogenic potential have no correlation with left or right side and gender.The latency and interphase of cervical vestibular evoked myogenic potentials increase with age,while the amplitude decreases with age.