脑胶质瘤伴发精神障碍的危险因素

The risk factors of mental disorders in glioma patients

目的探讨脑胶质瘤伴发精神障碍的危险因素。方法本研究纳入2020年4月~2023年1月94例脑胶质瘤患者为研究对象,观察患者是否发生精神障碍,并设为精神障碍组以及非精神障碍组。比较两组患者年龄、肿瘤位置、病理分级等资料,并以是否发生精神障碍为因变量,组间差异显著的资料为自变量,赋值后进行logistic回归分析。结果94例脑胶质瘤患者中有32例患者伴发精神障碍;精神障碍组相较非精神障碍组在年龄、肿瘤位置、病理分级、肿瘤与皮质关系等资料上的差异具有统计学意义(P<0.05);组间性别、文化程度差异无统计学意义(P>0.05);logistic回归分析显示,肿瘤位于额叶、颞叶是胶质瘤伴发精神障碍的危险因素。结论脑胶质瘤精神障碍发生率较高,肿瘤位于额叶、颞叶等会增加精神障碍发生风险。

Objective To explore the risk factors of mental disorders associated with glioma.Methods Ninetyfour patients with glioblastoma from April 2020 to January 2023 were selected in the study.whether the patient has developed mental disorders was observed,and they were divided into the mental disorder group and non mental disorder group.The age,tumor location,pathological grading,other data of two groups of patients were compared,and with the occurrence of mental disorders as the dependent variable,data with significant differences between groups as the independent variable.Perform logistic regression analysis were carried out after assigning values.Results Among ninety-four patients with glioma,32 patients had mental disorders.There were statistically significant differences in age,tumor location,pathological grading,and tumor cortical relationship between the mental disorder group and the non mental disorder group(P<0.05).There was no statistically significant difference in gender and educational level between groups(P>0.05).Logistic regression analysis showed that the location of tumors in the frontal and temporal lobes is a risk factor for glioma accompanied by mental disorders.Conclusion The incidence of mental disorders in gliomas is relatively high,and tumors located in the frontal and temporal lobes can increase the risk of mental disorders.