右美托咪定与舒芬太尼镇痛的联合应用在妇科手术中效果及对患者情绪的影响

The effect of dexmedetomidine combined with sufentanil analgesia in the gynecological surgery and to assess their effect on anxiety and depression

目的观察右美托咪定在妇科手术麻醉诱导期中与舒芬太尼镇痛的联合应用效果并评估其对焦虑抑郁情绪的影响。方法回顾性分析于我院(2021年01月-2023年01月)收治妇科手术患者500例,根据麻醉、镇痛药物选择方式不同进行分组,其中以右美托咪定在麻醉诱导期中与舒芬太尼镇痛250例患者为研究组,另生理盐水+舒芬太尼镇痛另250例作为对照组。结果在术后6h、12h、24h研究组疼痛评分及焦虑抑郁情绪评分较术后1h升高,而研究组低于对照组(P<0.05)。研究组并发症总发生率低于对照组,但术中心率降低率高于对照组(P<0.05)。结论在妇科手术中,以右美托咪定与舒芬太尼镇痛的联合应用,可显著平稳患者生命体征,提高麻醉效果,降低术后患者疼痛感与焦虑、抑郁的不良情绪。

Objective To observe the effect of dexmedetomidine and sufentanil analgesia in the induction period of gynecological surgery and to evaluate its effect on anxiety and depression.Methods A total of 500 gynecological surgery patients admitted to our hospital(01/2021-01/2023)were retrospectively analyzed and grouped according to the choice of anesthesia and analgesic drugs.250 patients with dexmedetomidine and sufentanil analgesia during induction of anesthesia were used as the study group,and another 250 patients with saline+sufentanil analgesia were used as the control group.Results Pain scores,anxiety and depression scores were higher in the study group at 6h,12h and 24h postoperatively compared with 1h postoperatively in two groups,while the study group was lower than the control group(P<0.05).The overall complication rate in the study group was lower than that in the control group,but the heart rate of reduction in the study group was higher than that in the control group,(P<0.05).Conclusion In gynecological surgery,the combined application of dexmedetomidine and sufentanil analgesia can significantly stabilize patients'vital signs,improve the anesthetic effect,and reduce postoperative patients'pain and adverse emotions of anxiety and depression.