坦索罗辛辅助输尿管镜下钬激光碎石术治疗输尿管结石的效果观察

Observation on the Effect of Tamsulosin Assisted Ureteroscopic Holmium Laser Lithotripsy in the Treatment of Ureteral Calculi

目的:分析输尿管镜下钬激光碎石术联合坦索罗辛治疗输尿管结石的疗效。方法:选取2021年10月—2022年10月福清市医院泌尿外科收治的88例输尿管结石患者,随机分为对照组与研究组,每组44例。对照组给予输尿管镜下钬激光碎石术治疗,研究组在对照组基础上给予坦索罗辛治疗。比较两组结石排净率、术后并发症、复发情况、术后康复用时及症状恢复情况。结果:研究组结石排净率为95.45%,高于对照组的81.82%(P<0.05);研究组并发症发生率、复发率低于对照组(P<0.05);研究组术后排气用时、下床用时、住院用时短于对照组(P<0.05);研究组术后附加问题、性问题、工作能力、整体健康状况、疼痛、尿路症状评分低于对照组(P<0.05)。结论:联合使用坦索罗辛可以进一步提升输尿管镜下钬激光碎石术的综合治疗效果,其对于患者预后具有积极的辅助价值,值得临床应用。

Objective:To analyze the efficacy of ureteroscopic holmium laser lithotripsy combined with tamsulosin in the treatment of ureteral calculi.Methods:A total of 88 patients with ureteral calculi admitted to the Department of Urology,Fuqing Hospital from October 2021 to October 2022 were randomly divided into control group and study group,with 44 patients in each group.The control group was treated with ureteroscopic holmium laser lithotripsy,and the study group was treated with tamsulosin on the basis of the control group.The stone clearance rate,postoperative complications,recurrence,postoperative rehabilitation time and symptom recovery were compared between the two groups.Results:The stone clearance rate of the study group was 95.45%,which was higher than 81.82%of the control group(P<0.05).The incidence of complications and recurrence rate in the study group were lower than those in the control group(P<0.05).The time of postoperative exhaust,getting out of bed and hospitalization in the study group were shorter than those in the control group(P<0.05).The scores of postoperative additional problems,sexual problems,working ability,overall health status,pain and urinary tract symptoms in the study group were lower than those in the control group(P<0.05).Conclusion:The combined use of tamsulosin can further improve the comprehensive treatment effect of ureteroscopic holmium laser lithotripsy,which has a positive auxiliary value for the recovery of patients’prognosis and health,and is worthy of clinical application.