从肺肝脾论治幽门螺杆菌感染性胃溃疡

Treatment of Helicobacter Pylori Infectious Gastric Ulcer from Lung,Liver and Spleen

胃溃疡为临床常见消化系统疾病,具有反复发作、缠绵难愈的特点,发病原因与胃酸、胃蛋白酶的侵袭作用与黏膜的防御能力间失去平衡,胃酸对黏膜产生自我消化成溃疡,幽门螺杆菌定植有关,临床上一线治疗方案常用质子泵抑制剂(PPI)或枸橼酸铋雷尼替丁加2种抗生素的三联疗法和质子泵抑制剂加铋剂加2种抗生素,以达到抑制胃酸、保护胃黏膜、抗菌消炎的作用,但不良作用多,长期使用可引起其他器官的病变。中医主要与湿浊内停客胃,影响肺、肝、脾功能有关,治疗当以燥湿行气为主。中医药在治疗方面具有一定优势和疗效。

Gastric ulcer is a common disease of digestive system in clinic.It has the characteristics of repeated attacks and difficult to cure.The pathogenesis is related to the loss of balance between the invasion of gastric acid and pepsin and the defense ability of mucosa,the self⁃digestion of gastric acid to mucosa into ulcers,and the colonization of Helicobacter pylori.In clinical treatment,proton pump inhibitor(PPI)or the triple therapy of ranitidine bismuth citrate,two antibiotics and proton pump inhibitor,bismuth and two antibiotics are commonly used to inhibit gastric acid,protect gastric mucosa,antibacterial and anti⁃inflammatory,but there are many side effects,and long⁃term use can cause lesions of other organs.Traditional Chinese medicine is mainly related to stopping stomach in dampness and affecting lung,liver and spleen function,and the treatment should be based on drying dampness and qi.Traditional Chinese medicine has certain advantages and curative effect in treatment.