从小肠脏腑功能异常探讨糖尿病视网膜病变病机与治疗

Approach to pathogenesis and treatment of diabetic retinopathy based on visceral dysfunction of small intestine

糖尿病视网膜病变是一种由糖尿病的慢性影响引起的微血管疾病,中医学认为其与目失濡养和浊毒内生密切相关。小肠有受盛化物和泌别清浊两大功能,受盛化物功能减退则精微生成减少,目失濡养;分清泌浊功能失常则脾散精乏源,浊毒内生。结合现代医学肠道菌群理论,认为小肠生理功能与肠道菌群调节作用相似,在糖尿病视网膜病变发生发展中起着重要作用。从小肠脏腑功能角度探讨糖尿病视网膜病变的发病机制和治疗方法,可为该病治疗提供新的思路。

Diabetic retinopathy is a kind of microvascular disease caused by the chronic affection of diabetes mellitus.Traditional Chinese medicine believes that it is closely related to eyes lossing nutrition and turbid toxin originating endogenously.The small intestine has two major functions:reservoir and transformation as well as separating the useful from the waste.If the function of reservoir and transformation decreases,the production of refined nutritious substance will decrease,which makes eyes lose nutrition.If the function of separating the useful from the waste is abnormal,the spleen will be able to disper essence poorly,which makes turbid toxin generate endogenously.Combined with the theory of intestinal flora in modern medicine,it is believed that the physiological function of small intestine is similar to regulating effect of intestinal flora,and plays an important role in the occurrence and development of diabetic retinopathy.It can provide a new idea for diagnosis and treatment of diabetic retinopathy to approach the pathogenesis and treatment of diabetic retinopathy based on visceral dysfunction of small intestine.