结直肠癌微卫星灶不稳定状态的影像学研究进展

Progress in imaging research on microsatellite instability of colorectal cancer

结直肠癌的微卫星灶不稳定(MSI)状态对病人的治疗方式及预后有显著影响,基于CT、MRI及PET/CT的影像组学和深度学习能够发现其潜在的影像特征,并可以无创性预测结直肠癌MSI状态,为临床医生制定合适的治疗方案提供依据。就CT、MRI及PET/CT预测结直肠癌MSI状态的研究进展予以综述。

The microsatellite instability(MSI)of colorectal cancer patients has a significant impact on their treatment strategy and prognosis.Basedon CT,MRI and PET/CT imagings,radiomics and deep learning(DL)can discover potential features of their medical images and can non-invasively predict the MSI of colorectal cancer,laying the foundation for clinicians to develop appropriate treatment plans.This article reviews the progress of CT,MRI,and PET/CT in predicting the MSI of colorectal cancer.