NRS2002营养风险筛查指导下的营养干预对肝硬化代偿期患者的影响

Effect of nutritional intervention guided by NRS2002 nutritional risk screening on patients with compensatory cirrhosis

目的 探究NRS2002营养风险筛查指导下的营养干预对肝硬化代偿期患者的影响。方法 选取2021年1月至12月南通大学附属南通第三医院、南通市第三人民医院中西医结合肝病科治疗的98例肝硬化患者为研究对象,采用随机数字表法将其分为对照组和观察组,各49例。对照组实施常规营养护理,观察组在此基础上实施NRS2002营养风险筛查指导下的营养干预。观察并比较两组干预前、干预8周后血清营养学指标水平、肝功能指标、并发症发生率情况。结果 干预后,两组血清白蛋白、转铁蛋白及前白蛋白水平高于干预前,且观察组高于对照组,差异有统计学意义(P<0.05);干预后,两组总胆红素、谷丙转氨酶水平低于干预前,且观察组低于对照组,凝血酶原活动度水平高于干预前,且观察组高于对照组,差异有统计学意义(P<0.05);观察组并发症总发生率低于对照组差异有统计学意义(P<0.05)。结论 NRS2002营养风险筛查指导下的营养干预可改善肝硬化患者的营养水平,保护肝功能,降低并发症的总发生率。

Objective To explore the effect of nutritional intervention guided by NRS2002 nutritional risk screening on patients with compensatory cirrhosis.Methods Ninety-eight patients with cirrhosis treated by the Department of Integrated Chinese and Western Medicine,Nantong Third Hospital Affiliated to Nantong University Nantong Third People’s Hospital from January 2021 to December 2021 were selected as the study objects,and they were divided into control group and observation group by random number table method,with 49 cases in each group.The control group received routine nutrition care,and the observation group received nutrition intervention guided by NRS2002 nutrition risk screening on this basis.The level of serum nutrition index,liver function index,and complication rate of the two groups were observed and compared before intervention and eight weeks after intervention.Results After intervention,the levels of serum albumin,transferrin,and prealbumin in two groups were higher than that before intervention,and those of the observation group were higher than those of the control group,the differences were statistically significant(P<0.05);after intervention,the levels of total bilirubin and alanine transaminase in two groups were lower than that before intervention,and those of the observation group were lower than those of the control group,and the level of prothrombin activity was higher than that before intervention,and the observation group was higher than that of the control group,the differences were statistically significant(P<0.05);the total complication rate of observation group was lower than that of control group,the differences were statistically significant(P<0.05).Conclusion Nutrition assessment and management can improve the nutritional level,protect liver function and reduce the risk of complications.