血液透析共病且多重用药患者感知药物负担现状及影响因素分析

The current status and influencing factors of perceived medication-related burden in hemodialysis patients with multimorbidity and polypharmacy

目的了解血液透析共病且多重用药患者感知药物负担水平,并分析其影响因素。方法便利抽取2021年7月至2022年2月于南宁市3所三级甲等医院门诊的283例血液透析共病且多重用药患者为调查对象。采用一般资料调查表、用药生活问卷、慢性病患者健康素养量表和医疗社会支持量表进行调查。结果血液透析共病且多重用药患者药物负担得分(106.30±14.99)分。多元线性回归分析结果显示,年龄、水肿程度、社会支持是药物负担的影响因素。结论血液透析共病且多重用药患者感知药物负担处于中度偏低水平,受年龄、水肿程度、社会支持影响。提示护理人员应根据患者的年龄、水肿程度、社会支持情况,针对性地对患者进行干预,以期减轻患者药物负担。

Objective To understand the current status of perceived medication-related burden in hemodialysis(HD)patients with multimorbidity and polypharmacy,and to analyze the influencing factors.Methods Using a convenience sampling method,283 HD patients with multimorbidity and polypharmacy from the outpatient department of 3 tertiary hospitals in Nanning city from July 2021 to February 2022 were selected as participants.The general information questionnaire,Living with Medicines Questionnaire(LMQ),Health Literacy Management Scale,Medical Outcomes Study Social Support Survey were used for investigation.Results The total score of LMQ in patients with multimorbidity and polypharmacy was(106.30±14.99).Multiple linear regression analysis revealed that age,grade of edema and social support were the influencing factors of medication-related burden.Conclusion The medication-related burden in hemodialysis patients with multimorbidity and polypharmacy is at a moderately low level,and was affected by age,edema degree and social support.It is suggested that nurses should target interventions to patients according to their age,degree of edema,and social support with the aim of reducing their medication burden.