急性心肌梗死新型标志物的相关研究进展

Research progress on new markers of acute myocardial infarction

急性心肌梗死属于高发且危害严重的心血管系统疾病,心肌生物标志物在急性心肌梗死的诊断及病情的发生发展中起到重要作用,例如肌酸激酶同工酶、肌钙蛋白T/I、脑钠肽等。近年,出现一些可溶性生长刺激表达基因2蛋白、生长分化因子-15、半乳糖凝集素-3和miRNA等新型生物标志物,可对心血管急性事件的的预后进行预测。本文就通过探讨上述新型心脏标志物与急性心肌梗死发生发展的相关性,以期为临床医师提供帮助。

Acute myocardial infarction is a cardiovascular disease with high incidence and serious harm.Myocardial biomarkers,such as creatine kinase isoenzyme,troponin T/I,brain natriuretic peptide and so on,play an important role in the diagnosis and development of acute myocardial infarction.In recent years,some new biomarkers,such as soluble growth stimulating expression gene 2 protein,growth differentiation factor-15,galectin-3 and miRNA,etc.have emerged in predicting the prognosis of acute cardiovascular events.This article discusses the correlation between the above new cardiac markers and the occurrence and development of acute myocardial infarction,in order to provide help for clinicians.