隔日禁食在慢性疾病中的研究进展

Research Progress of Alternate-day Fasting in Chronic Diseases

慢性疾病逐渐成为我国居民死亡的首位原因,给社会造成巨大的负担。饮食控制是对慢性疾病管理的重要方式。隔日禁食(alternate-day fasting,ADF)是一种禁食日与自由进食日交替进行的新兴饮食模式。此综述通过分析隔日禁食在慢性疾病的文献,发现隔日禁食在预防和改善神经系统疾病、心血管疾病、肿瘤、代谢性疾病等方面有着积极影响。目前隔日禁食的研究仍是在动物方面较多,广泛的推广需更多的临床随机试验,评估其安全性、有效性和依从性。

Chronic diseases have gradually become the first cause of death in our country,causing huge social burden.Diet control is an important way for the management of chronic diseases.Alternate-day fasting(ADF)is a new dietary pattern that alternates between fasting days with free-eating days.This review analyzes the literature on alternate-day fasting in chronic diseases,and finds that alternate-day fasting has a positive effect on the prevention and improvement of neurological disorder diseases,cardiovascular diseases,cancers,metabolic diseases and so on.At present,the study of alternate-day fasting is still more in animals,and more clinical randomized trials are need to evaluate its safety,effectiveness,and compliance.