摘要
目的探讨38℃恒温保存时间对3种手术冲洗液安全性的影响。方法选择中南大学湘雅医学院附属海口医院2022年1月购买的袋装0.9%氯化钠溶液、袋装电切液、袋装等渗液各480袋作为本次实验的研究对象。将3种手术冲洗液各480袋各自随机分为6组,其中一组室温(21~25℃)存放7 d进行安全指标检测,作为空白对照组,另外5组加温到38℃后分别保存2 d、7 d、14 d、21 d、28 d后进行安全性指标检测,组间数据采用单因素方差分析。结果加热2 d组、7 d组、14 d组、21 d组、28 d组的0.9%氯化钠溶液pH值、渗透压摩尔浓度均高于空白对照组,组间比较差异均有统计学意义(F=2.46、2.84,均P<0.05);加热2 d组、7 d组、14 d组、21 d组、28 d组的电切液pH值、渗透压摩尔浓度均高于空白对照组,组间比较差异均有统计学意义(F=6.41、14.32,均P<0.05);加热2 d组、7 d组、14 d组、21 d组、28 d组的等渗液pH值、渗透压摩尔浓度均高于空白对照组,差异均有统计学意义(F=9.07、14.91,均P<0.05);3种冲洗液空白对照组、加热2 d组、加热7 d组、加热14 d组、加热21 d组、加热28 d组细菌学培养均为阴性,且冲洗液外观无明显变化,无分层、浑浊、沉淀、挂壁及异味。结论9%氯化钠溶液、袋装电切液、袋装等渗液经38℃恒温存放28 d后pH和渗透压摩尔浓度均有所增加,但都在安全范围内,同时3种冲洗液均能保持无菌状态,溶液无分层、浑浊、沉淀、挂壁及异味等情况,临床可安全使用。
Objective To investigate the effect of 38℃thermostatic storage time on the safety of three surgical flushers.Methods In January 2022,Haikou Hospital Affiliated to Xiangya Medical College,Zhongnan University purchased 0.9%sodium chloride solution in bags,electrocutting solution in bags,and other exhalative solution in bags 480 bags for each as the research objects of this experiment.Four hundred and eighty bags of each of the three surgical flushing solutions were randomly divided into 6 groups.One group was stored at room temperature(21~25℃)for 7 days for safety index detection and was set as a blank control group;the other five groups were stored at 38℃for 2,7,14,21,and 28 days,respectively,for safety index detection.One-way analysis of variance was used to compare the data between the groups.Results The pH values and osmolal pressures of 0.9%sodium chloride solution in the 2,7,14,21,and 28-day heating groups were higher than those in the blank control group,with statistical differences between the groups(F=2.46 and 2.84;both P<0.05).The pH values and osmotic pressure molar concentrations of electrolysis solution in the 2,7,14,21,and 28-day heating groups were higher than those in the blank control group,with statistical differences between the groups(F=6.41 and 14.32;both P<0.05).The pH values and osmotic pressure molar concentrations of exudative solution in the 2,7,14,21,and 28-day heating groups were higher than those in the blank control group,with statistical differences between the groups(F=9.07 and 14.91;both P<0.05).The bacteria culture was negative in all the 3 fluids in the blank control group and the 2,7,14,21,and 28-day heating groups;the appearance of the 3 fluids had no obvious changes;no stratification,turbidity,precipitation,wall hanging,or abnormal odor were found in the 3 fluids.Conclusions After being stored at 38℃for 28 days,the pH values and osmotic pressure molar concentrations of 9%sodium chloride solution,bag electrolysis solution,and bag exudative solution increased,but all of them were within the safe ranges.At the same time,the three kinds of rinsing solution can maintain the aseptic state,without any stratification,turbidity,precipitation,wall hanging,and abnormal odor,so they can be used safely in clinic.
作者
王波
蒙漫史
陈夏明
陈翠完
蒙薇好
Wang Bo;Meng Manshi;Chen Xiaming;Chen Cuiwan;Meng Weihao(Operation Room,Haikou Hospital Affiliated to Xiangya Medical College,Zhongnan Uiniversity,Haikou 570208,China;Nursing Department,Haikou Hospital Affiliated to Xiangya Medical College,Zhongnan Uiniversity,Haikou 570208,China;Clinical Laboratory,Haikou Hospital Affiliated to Xiangya Medical College,Zhongnan Uiniversity,Haikou 570208,China)
出处
《国际医药卫生导报》
2024年第1期91-94,共4页
International Medicine and Health Guidance News
基金
海南省卫生健康科研行业科研项目(21A200328)。
关键词
手术冲洗液
保存时间
恒温
安全性
Surgical flushing solution
Storage time
Constant temperature
Safety